Preventative delivery of IL-35 by Lactococcus lactis ameliorates DSS-induced colitis in mice

J Wang, M Tian, W Li, F Hao - Applied microbiology and biotechnology, 2019 - Springer
Ulcerative colitis (UC) is one of the two major forms of inflammatory bowel disease (IBD)
characterized by superficial mucosal inflammation, rectal bleeding, diarrhea, and abdominal …

HIC1 interacts with FOXP3 multi protein complex: Novel pleiotropic mechanisms to regulate human regulatory T cell differentiation and function

SBA Andrabi, K Batkulwar, SD Bhosale, R Moulder… - Immunology …, 2023 - Elsevier
Transcriptional repressor, hypermethylated in cancer 1 (HIC1) participates in a range of
important biological processes, such as tumor repression, immune suppression, embryonic …

[HTML][HTML] THBS1+ myeloid cells expand in SLD hepatocellular carcinoma and contribute to immunosuppression and unfavorable prognosis through TREM1

J Giraud, D Chalopin, E Ramel, T Boyer, A Zouine… - Cell Reports, 2024 - cell.com
Hepatocellular carcinoma (HCC) is an inflammation-associated cancer arising from viral or
non-viral etiologies including steatotic liver diseases (SLDs). Expansion of …

Profound downregulation of neural transcription factor Npas4 and Nr4a family in fetal mice neurons infected with Zika virus

SP Alpuche-Lazcano, J Saliba, VV Costa… - PLoS Neglected …, 2021 - journals.plos.org
Zika virus (ZIKV) infection of neurons leads to neurological complications and congenital
malformations of the brain of neonates. To date, ZIKV mechanism of infection and …

Hydroxychloroquine improves motor function and affords neuroprotection without inhibition of inflammation and autophagy in mice after intracerebral hemorrhage

A Yoshimizu, K Kinoshita, Y Ichihara, Y Kurauchi… - Journal of …, 2022 - Elsevier
We examined the effect of an immunomodulator hydroxychloroquine, also known as a Nurr1
ligand and an autophagy inhibitor, on a mouse model of intracerebral hemorrhage (ICH) …

Nuclear receptors of the NR4a family are not required for the development and function of follicular T helper cells

W Ma, R Zhao, R Yang, B Liu, X Chen, L Wu… - International …, 2015 - Elsevier
Follicular T helper (Tfh) cells promote germinal center (GC) reaction and high-affinity
antibody production. The molecular mechanisms that regulate development and function of …

HIC1 interacts with FOXP3 multi protein complex: a novel mechanism to regulate human regulatory T cell differentiation and function

SB Ahmad Andrabi, K Batkulwar, SD Bhosale… - bioRxiv, 2023 - biorxiv.org
Transcriptional repressor, hypermethylated in cancer 1 (HIC1) participates in a range of
important biological processes, such as tumor repression, immune suppression, embryonic …

[PDF][PDF] Función del receptor nuclear Nurr1 en los macrófagos humanos polarizados

MÁ Solís Barbosa - 2024 - repositorio.cinvestav.mx
Los macrófagos (Mϕs) son células heterogéneas del sistema inmune innato con una
elevada plasticidad y versatilidad. Presentan una gran diversidad de funciones …

Étude du rôle de l'expression de l'intégrine αvβ8 par les lymphocytes T régulateurs dans la réponse anti-tumorale

A Lainé - 2019 - theses.hal.science
Les tumeurs solides emploient diverses stratégies afin de se maintenir dans l'organisme et
d'échapper à l'inhibition du système immunitaire. Un des mécanismes les plus puissants est …