Chagas disease (CD) is a vector-borne Neglected Zoonotic Disease (NZD) caused by a
flagellate protozoan, Trypanosoma cruzi, that affects various mammalian species across …

Chagas disease is a major neglected tropical disease, transmitted predominantly by
triatomine insect vectors, but also through congenital and oral routes. While endemic in the …

We review the epidemiological role of domestic and commensal hosts of Trypanosoma cruzi
using a quantitative approach, and compiled> 400 reports on their natural infection. We link …

Trypanosoma cruzi is the agent of Chagas disease, transmitted by hematophagous
triatomine vectors. Establishing transmission cycles is key to understand the epidemiology of …

Trypanosoma cruzi infection causes Chagas disease, which affects 7 million people
worldwide. Two drugs are available to treat it: benznidazole and nifurtimox. Although both …

An estimated 7–8 million people are infected worldwide with almost all of the cases
occurring in the Americas, predominantly in the poorest countries in the region [2–4] …

Chagas disease, or American trypanosomiasis, which is caused by the protozoan parasite
Trypanosoma cruzi, is primarily a vector disease endemic in 21 Latin American countries …

Background Chagas disease is a zoonotic disease caused by the protozoan parasite
Trypanosoma cruzi. The role of dogs as sentinels has been proposed in multiple regions, as …

Introduction Chronic infection with the protozoal parasite Trypanosoma cruzi leads to a
progressive cardiac disease, known as chronic Chagasic cardiomyopathy (CCC). A new …

During Trypanosoma cruzi infection, macrophages phagocytose parasites and remove
apoptotic cells through efferocytosis. While macrophage 1 (M1) produces proinflammatory …