Limb‐girdle muscular dystrophies (LGMDs) are a highly heterogeneous group of
neuromuscular disorders that are associated with weakness and wasting of muscles in legs …

Sarcoglycanopathies are the most severe forms of autosomal recessive limb-girdle muscular
dystrophies (LGMDs), constituting about 10–25% of LGMDs. The clinical phenotype is …

Muscular dystrophies are a heterogeneous group of monogenic neuromuscular disorders
which lead to progressive muscle loss and degeneration of the musculoskeletal system. The …

As the dimensionality and complexity of datasets increase, such as biological data, the
demand for fast and efficient technologies to detect relevant feature information from these …

The spectrum of canine muscular dystrophies has rapidly grown with the recent identification
of several more affected breeds and associated mutations. Defects include those in genes …

Over 94 million domestic cats are susceptible to cancers and other common and rare
diseases. Whole exome sequencing (WES) is a proven strategy to study these disease …

Alzheimer's disease (AD) is a complex neurodegenerative disorder that affects thinking,
memory, and behavior. Limbic-predominant age-related TDP-43 encephalopathy (LATE) is …

Swallowing impairment is a highly prevalent and clinically significant problem affecting
people and dogs. There are myriad causes of swallowing impairment of which …

Abstract Background Boys with Duchenne muscular dystrophy (DMD) have DMD gene
mutations, with associated loss of the dystrophin protein and progressive muscle …

An 8-month-old female Lagotto Romagnolo dog was presented for a 1-month history of an
initial severe reluctance to move, rapidly progressing to a marked stiff gait and progressive …