Idiopathic inflammatory myopathies

IE Lundberg, M Fujimoto, J Vencovsky… - Nature Reviews …, 2021 - nature.com
Idiopathic inflammatory myopathies (IIM), also known as myositis, are a heterogeneous
group of autoimmune disorders with varying clinical manifestations, treatment responses …

Dermatomyositis: clinical features and pathogenesis

ME DeWane, R Waldman, J Lu - Journal of the American Academy of …, 2020 - Elsevier
Dermatomyositis (DM) is an idiopathic inflammatory myopathy that is clinically
heterogeneous and that can be difficult to diagnose. Cutaneous manifestations sometimes …

Myositis‐specific autoantibodies: an important tool to support diagnosis of myositis

Z Betteridge, N McHugh - Journal of internal medicine, 2016 - Wiley Online Library
The idiopathic inflammatory myopathies are characterized by muscle weakness, skin
disease and internal organ involvement. Autoimmunity is known to have a role in myositis …

Current classification and management of inflammatory myopathies

J Schmidt - Journal of neuromuscular diseases, 2018 - content.iospress.com
Inflammatory disorders of the skeletal muscle include polymyositis (PM), dermatomyositis
(DM),(immune mediated) necrotizing myopathy (NM), overlap syndrome with myositis …

A comprehensive overview on myositis-specific antibodies: new and old biomarkers in idiopathic inflammatory myopathy

M Satoh, S Tanaka, A Ceribelli, SJ Calise… - Clinical reviews in …, 2017 - Springer
Autoantibodies specific for idiopathic inflammatory myopathy (myositis-specific
autoantibodies (MSAs)) are clinically useful biomarkers to help the diagnosis of …

Autoantibodies in myositis

NJ McHugh, SL Tansley - Nature Reviews Rheumatology, 2018 - nature.com
The discovery of novel autoantigen systems related to idiopathic inflammatory myopathies
(collectively referred to as myositis) in adults and children has had major implications for the …

Rituximab in the treatment of refractory adult and juvenile dermatomyositis and adult polymyositis: a randomized, placebo‐phase trial

CV Oddis, AM Reed, R Aggarwal, LG Rider… - Arthritis & …, 2013 - Wiley Online Library
Objective To assess the safety and efficacy of rituximab in a randomized, double‐blind,
placebo‐phase trial in adult and pediatric myositis patients. Methods Adults with refractory …

Most patients with cancer‐associated dermatomyositis have antibodies to nuclear matrix protein NXP‐2 or transcription intermediary factor 1γ

DF Fiorentino, LS Chung… - Arthritis & …, 2013 - Wiley Online Library
Objective Since dermatomyositis (DM) is associated with an increased risk of malignancy,
accurate identification of patients likely to harbor cancers is important. Using …

Common and distinct clinical features in adult patients with anti-aminoacyl-tRNA synthetase antibodies: heterogeneity within the syndrome

Y Hamaguchi, M Fujimoto, T Matsushita, K Kaji… - PloS one, 2013 - journals.plos.org
Objective To identify similarities and differences in the clinical features of adult Japanese
patients with individual anti-aminoacyl-tRNA synthetase antibodies (anti-ARS Abs). Methods …

RNA helicase encoded by melanoma differentiation–associated gene 5 is a major autoantigen in patients with clinically amyopathic dermatomyositis: association with …

S Sato, K Hoshino, T Satoh, T Fujita… - … : Official Journal of …, 2009 - Wiley Online Library
Objective To identify the autoantigen recognized by the autoantibody that is associated with
clinically amyopathic dermatomyositis (C‐ADM) and rapidly progressive interstitial lung …