3 minutes to precisely measure morphogen concentration

T Lucas, H Tran, CA Perez Romero, A Guillou… - PLoS …, 2018 - journals.plos.org
Morphogen gradients provide concentration-dependent positional information along polarity
axes. Although the dynamics of the establishment of these gradients is well described …

Synthetic reconstruction of the hunchback promoter specifies the role of Bicoid, Zelda and Hunchback in the dynamics of its transcription

G Fernandes, H Tran, M Andrieu, Y Diaw, CP Romero… - Elife, 2022 - elifesciences.org
For over 40 years, the Bicoid-hunchback (Bcd-hb) system in the fruit fly embryo has been
used as a model to study how positional information in morphogen concentration gradients …

Lighting Up Gene Activation in Living Drosophila Embryos

C Fernandez, M Lagha - Imaging Gene Expression: Methods and …, 2019 - Springer
With its rapid development, ease of collection, and the presence of a unique layer of nuclei
located close to the surface, the Drosophila syncytial embryo is ideally suited to study the …

MitoTrack, a user-friendly semi-automatic software for lineage tracking in living embryos

A Trullo, J Dufourt, M Lagha - Bioinformatics, 2020 - academic.oup.com
Motivation During development, progenitor cells undergo multiple rounds of cellular
divisions during which transcriptional programs must be faithfully propagated. Investigating …

Synthetic deconstruction of hunchback regulation by Bicoid

G Fernandes, H Tran, M Andrieu, Y Diaw… - bioRxiv, 2021 - biorxiv.org
During development, cell identity is established reproducibly among individuals through the
expression of specific genes at the correct time and correct location in space. How genes …