Therapeutic antibodies targeting disease-associated antigens are key tools in the treatment
of cancer and autoimmunity. So far, therapeutic antibodies have targeted antigens that are …

Immunomodulation is a molecular technique that allows the interference with cellular
metabolism or pathogen infectivity by the ectopic expression of genes encoding antibodies …

Human papillomavirus (HPV)‐associated tumors still represent an urgent problem of public
health in spite of the efficacy of the prophylactic HPV vaccines. Specific antibodies in single …

Aggregation of TAR DNA-binding protein of 43 kDa (TDP-43) is implicated in the
pathogenesis of sporadic and certain familial forms of amyotrophic lateral sclerosis (ALS) …

Single-chain Fv antibody fragments (scFv) represent a convenient antibody format for
intracellular expression in eukaryotic or prokaryotic cells. These so-called intrabodies have …

Background Intrabodies are defined as antibody molecules which are ectopically expressed
inside the cell. Such intrabodies can be used to visualize or inhibit the targeted antigen in …

Current concepts regarding the pathogenesis of Parkinson's disease support a model
whereby environmental factors conspire with a permissive genetic background to initiate the …

The specific and high affinity binding properties of intracellular antibodies (intrabodies),
combined with their ability to be stably expressed in defined organelles, provides powerful …

We have compiled a comprehensive list of the articles published in the year 2000 that
describe work employing commercial optical biosensors. Selected reviews of interest for the …

Targeting cytoplasmic protein–protein interactions with antibodies remains technically
challenging, since antibodies expressed in the cytosol frequently form insoluble aggregates …