The expression of the human Ki‐67 protein is strictly associated with cell proliferation.
During interphase, the antigen can be exclusively detected within the nucleus, whereas in …

Ki67 protein: the immaculate deception? This article updates our previous review of Ki67
published in Histopathology 10 years ago. In this period the numbers of papers published …

The proliferation marker Ki-67 is one of the most controversially discussed parameters for
treatment decisions in breast cancer patients. The purpose of this study was to evaluate the …

Background Gene expression profiling of breast cancer has identified two biologically
distinct estrogen receptor (ER)-positive subtypes of breast cancer: luminal A and luminal B …

The Ki-67 antigen is used to evaluate the proliferative activity of breast cancer (BC);
however, Ki-67's role as a prognostic marker in BC is still undefined. In order to better define …

We have performed a systematic review and meta-analysis of proliferation markers (Ki-67,
mitotic index (MI), proliferating cell nuclear antigen (PCNA) and thymidine or …

Purpose To evaluate the prognostic and predictive value of Ki-67 labeling index (LI) in a trial
comparing letrozole (Let) with tamoxifen (Tam) as adjuvant therapy in postmenopausal …

In the last few decades, proliferative markers have been broadly evaluated as prognostic
and predictive factors for early stage breast cancer patients. Several papers evaluating one …

Several small studies have reported that having a high percentage of breast tumor cells that
express the proliferation antigen Ki-67 (ie, a high Ki-67 labeling index) predicts better …

Purpose: The bone marrow is a frequent and clinically important homing site for early
disseminated breast cancer cells. Here, we aimed to profile the protein expression of these …