The ever-growing availability of high-quality genotypes for a multitude of species has
enabled researchers to explore the underlying genetic architecture of complex phenotypes …

Genome-wide association studies (GWAS) are integral for studying genotype-phenotype
relationships and gaining a deeper understanding of the genetic architecture underlying trait …

The ubiquity of nonparental hybrid phenotypes, such as hybrid vigor and hybrid inferiority,
has interested biologists for over a century and is of considerable agricultural importance …

We introduce the localized Lasso, which learns models that both are interpretable and have
a high predictive power in problems with high dimensionality d and small sample size n …

Background Inferring gene networks from high-throughput data constitutes an important step
in the discovery of relevant regulatory relationships in organism cells. Despite the large …

Genome-wide association studies (GWAS) are a powerful tool to elucidate the genotype–
phenotype map. Although GWAS are usually used to assess simple univariate associations …

Phenotypic heritability of complex traits and diseases is seldom explained by individual
genetic variants identified in genome-wide association studies (GWAS). Many methods have …

This paper investigates the effectiveness of transfer learning based on information criteria.
We propose a procedure that combines transfer learning with Mallows' Cp (TLCp) and prove …

Identifying measurable genetic indicators (or biomarkers) of a specific condition of a
biological system is a key element of precision medicine. Indeed it allows to tailor diagnostic …

Biology is orchestrated by a myriad of beautifully complex phenomena. While scientists have
only been able to uncover a tiny part of all existing biological mechanisms, they have done …