Background: Contemporary studies suggest that familial hypercholesterolemia (FH) is more
frequent than previously reported and increasingly recognized as affecting individuals of all …

Abstract Purpose of Review This review aims to summarize the existing research on sex
differences in familial hypercholesterolemia (FH) across the lifespan. Recent Findings From …

Lipid disorders play a critical role in the intricate development of atherosclerosis and its
clinical consequences, such as coronary heart disease and stroke. These disorders are …

Familial hypercholesterolemia (FH) is the most common monogenic disorder associated
with premature atherosclerotic cardiovascular disease. Early diagnosis and effective …

Background Current data from individual studies present conflicting evidence about the
relationship between risk factors and cardiovascular disease (CVD) in heterozygous familial …

Familial hypercholesterolemia (FH) is a common genetic cause of premature cardiovascular
disease (CVD). The reported prevalence rates for both heterozygous FH (HeFH) and …

Objective Overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in
endothelium leads to arterial calcification in mice. The purpose of this study was to examine …

Familial hypercholesterolemia (FH) is an autosomal dominant disease that has a prevalence
of approximately 1/250 inhabitants and is the most frequent cause of early coronary heart …

Background and aims Familial hypercholesterolemia (FH) is a genetic disorder associated
with high cardiovascular burden of disease. FH prevalence may vary widely across …

A group of experts convened by the Spanish Society of Arteriosclerosis (SEA) has been in
charge of updating the SEA document on the indications of PCSK9 inhibitors (PCSK9i) in …