Membrane transporters involved in iron trafficking: physiological and pathological aspects

A Pasquadibisceglie, MC Bonaccorsi di Patti, G Musci… - Biomolecules, 2023 - mdpi.com
Iron is an essential transition metal for its involvement in several crucial biological functions,
the most notable being oxygen storage and transport. Due to its high reactivity and potential …

Structures and coordination chemistry of transporters involved in manganese and iron homeostasis

S Ray, R Gaudet - Biochemical Society Transactions, 2023 - portlandpress.com
A repertoire of transporters plays a crucial role in maintaining homeostasis of biologically
essential transition metals, manganese, and iron, thus ensuring cell viability. Elucidating the …

Jasmonic acid's impact on Sedum alfredii growth and cadmium tolerance: A physiological and transcriptomic study

A Shi, J Xu, Y Guo, C Rensing, J Chang… - Science of The Total …, 2024 - Elsevier
Soil cadmium (Cd) pollution is escalating, necessitating effective remediation strategies.
This study investigated the effects of exogenous jasmonic acid (JA) on Sedum alfredii Hance …

[HTML][HTML] The Manganese–Bone Connection: Investigating the Role of Manganese in Bone Health

G Taskozhina, G Batyrova, G Umarova… - Journal of Clinical …, 2024 - mdpi.com
The complex relationship between trace elements and skeletal health has received
increasing attention in the scientific community. Among these minerals, manganese (Mn) …

[HTML][HTML] In vitro reconstitution of transition metal transporters

EL Ongey, A Banerjee - Journal of Biological Chemistry, 2024 - Elsevier
Transition metal ions are critically important across all kingdoms of life. The chemical
properties of iron, copper, zinc, manganese, cobalt, and nickel make them very attractive for …

[HTML][HTML] Slc11 Synapomorphy: A Conserved 3D Framework Articulating Carrier Conformation Switch

MFM Cellier - International Journal of Molecular Sciences, 2023 - mdpi.com
Transmembrane carriers of the Slc11 family catalyze proton (H+)-dependent uptake of
divalent metal ions (Me2+) such as manganese and iron—vital elements coveted during …

Fe(II), Mn(II), and Zn(II) Binding to the C-Terminal Region of FeoB Protein: An Insight into the Coordination Chemistry and Specificity of the Escherichia coli Fe(II) …

B Orzel, A Pelucelli, M Ostrowska, S Potocki… - Inorganic …, 2023 - ACS Publications
The interactions between two peptide ligands [Ac763CCAASTTGDCH773 (P1) and Ac743RRARSRVDIELLATRKSVSSCCAAS…
(P2)] derived from the cytoplasmic C-terminal region of Eschericha coli FeoB protein and Fe …

Structural insights into ferroportin mediated iron transport

M Jormakka - Biochemical Society Transactions, 2023 - portlandpress.com
Iron is a vital trace element for almost all organisms, and maintaining iron homeostasis is
critical for human health. In mammals, the only known gatekeeper between intestinally …

Structure-based virtual screening of Trachyspermum ammi metabolites targeting acetylcholinesterase for Alzheimer's disease treatment

MS Musa, MT Islam, W Billah, MS Hossain, MSS Rahat… - PloS one, 2024 - journals.plos.org
In recent decades, Alzheimer's disease (AD) has garnered significant attention due to its
rapid global prevalence. The cholinergic hypothesis posits that the degradation of …

[HTML][HTML] In silico evaluation of anti-colorectal cancer inhibitors by Resveratrol derivatives targeting Armadillo repeats domain of APC: molecular docking and molecular …

S Akash, MR Islam, AA Bhuiyan, MN Islam… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Colorectal cancer is the second leading cause of cancer-related deaths. In 2018, there were
an estimated 1.8 million cases, and this number is expected to increase to 2.2 million by …