International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma

S Kumar, B Paiva, KC Anderson, B Durie… - The lancet …, 2016 - thelancet.com
Treatment of multiple myeloma has substantially changed over the past decade with the
introduction of several classes of new effective drugs that have greatly improved the rates …

Prognostic and predictive biomarker developments in multiple myeloma

CT Wallington-Beddoe, RL Mynott - Journal of hematology & oncology, 2021 - Springer
New approaches to stratify multiple myeloma patients based on prognosis and therapeutic
decision-making, or prediction, are needed since patients are currently managed in a similar …

Measurable residual disease by next-generation flow cytometry in multiple myeloma

B Paiva, N Puig, MT Cedena, L Rosiñol… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Assessing measurable residual disease (MRD) has become standard with many
tumors, but the clinical meaning of MRD in multiple myeloma (MM) remains uncertain …

Current status of autologous stem cell transplantation for multiple myeloma

R Al Hamed, AH Bazarbachi, F Malard… - Blood cancer …, 2019 - nature.com
More than 30 years after its introduction, autologous stem cell transplantation (ASCT)
remains the standard of care for young patients with newly diagnosed multiple myeloma. Not …

Depth of response in multiple myeloma: a pooled analysis of three PETHEMA/GEM clinical trials

JJ Lahuerta, B Paiva, MB Vidriales, L Cordón… - Journal of Clinical …, 2017 - ascopubs.org
Purpose To perform a critical analysis on the impact of depth of response in newly
diagnosed multiple myeloma (MM). Patients and Methods Data were analyzed from 609 …

Lenalidomide after stem-cell transplantation for multiple myeloma

PL McCarthy, K Owzar, CC Hofmeister… - … England Journal of …, 2012 - Mass Medical Soc
Background Data are lacking on whether lenalidomide maintenance therapy prolongs the
time to disease progression after autologous hematopoietic stem-cell transplantation in …

IMWG consensus on risk stratification in multiple myeloma

WJ Chng, A Dispenzieri, CS Chim, R Fonseca… - Leukemia, 2014 - nature.com
Multiple myeloma is characterized by underlying clinical and biological heterogeneity, which
translates to variable response to treatment and outcome. With the recent increase in …

Prognostic value of deep sequencing method for minimal residual disease detection in multiple myeloma

J Martinez-Lopez, JJ Lahuerta, F Pepin… - Blood, The Journal …, 2014 - ashpublications.org
We assessed the prognostic value of minimal residual disease (MRD) detection in multiple
myeloma (MM) patients using a sequencing-based platform in bone marrow samples from …

New criteria for response assessment: role of minimal residual disease in multiple myeloma

B Paiva, JJM Van Dongen… - Blood, The Journal of the …, 2015 - ashpublications.org
Assessment of minimal residual disease (MRD) is becoming standard diagnostic care for
potentially curable neoplasms such as acute lymphoblastic leukemia. In multiple myeloma …

Frontline therapy of multiple myeloma

P Moreau, M Attal, T Facon - … Journal of the American Society of …, 2015 - ashpublications.org
In the past decade, one of the major advances in the management of patients with
symptomatic newly diagnosed multiple myeloma has been the introduction of novel agents …