Neuroprotective and neurorestorative therapy represent two major drug intervention
strategies for ischemic stroke. Multiple factors such as excitotoxicity, inflammation …

Abstract Silent information regulator 1 (SIRT1) is a ubiquitously expressed protein and has
an intricate role in the pathology, progression, and treatment of several diseases. SIRT1 is a …

Abstract Ethnopharmacological relevance Panax notoginseng (Burk.) FH Chen, also called
Sanqi, is a widely used traditional Chinese medicine, which has long history used as herbal …

Chronic wounds such as diabetic feet undergo a lifetime risk of developing into incurable
ulcers. Current treatments for chronic wounds remain unsatisfactory due to the lack of ideal …

Panax notoginseng (Burk) FH Chen, as traditional Chinese medicine, has a long history of
high clinical value, such as anti-inflammatory, anti-oxidation, inhibition of platelet …

Background: The mammalian circadian clock and its associated clock genes are
increasingly been recognized as critical components for a number of physiological and …

The global increase in lifespan noted not only in developed nations, but also in large
developing countries parallels an observed increase in a significant number of non …

Many phytochemicals demonstrate nonmonotonic dose/concentration-response termed
biphasic dose-response and are considered to be hormetic compounds, ie, they induce …

Amyotrophic lateral sclerosis (ALS) is a chronic neurodegenerative disease with poor
prognosis. The intricacies surrounding its pathophysiology could partly account for the lack …

Background Mitochondrial autophagy maintains mitochondrial function and cellular
homeostasis and plays a critical role in the pathological process of cerebral …