Excited (triplet) states offer a myriad of attractive synthetic pathways, including
cycloadditions, selective homolytic bond cleavages and strain-release chemistry …

The concept of strain in organic compounds is as old as modern organic chemistry and was
initially introduced to justify the synthetic setbacks along the synthesis of small ring systems …

Dearomative photocycloadditions are valuable chemical transformations, serving as an
efficient platform to create three-dimensional molecular complexity. However, the …

Dearomatization reactions provide rapid access to structurally complex three-dimensional
molecules from simple aromatic compounds. Plenty of reports have demonstrated their …

Artificial photosynthesis of H2O2 using earth-abundant water and oxygen is a promising
approach to achieve scalable and cost-effective solar fuel production. Recent studies on this …

Benzenes, the most ubiquitous structural moiety in marketed small-molecule drugs, are
frequently associated with poor 'drug-like'properties, including metabolic instability, and poor …

Abstract β-Amino acids are frequently found as important components in numerous
biologically active molecules, drugs and natural products. In particular, they are broadly …

Conspectus Exploring the enormous chemical space through an expedient building-up of
molecular diversity is an important goal of organic chemistry. The development of synthetic …

Discovery chemists routinely identify purpose-tailored molecules through an iterative
structural optimization approach, but the preparation of each successive candidate in a …

Dearomative photocycloaddition of monocyclic arenes is an appealing strategy for
comprehending the concept of “escape from flatland”. This brings the replacement of readily …