Clinical practice guideline by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America: 2021 guideline on diagnosis and management …

CR Woods, JS Bradley, A Chatterjee… - Journal of the …, 2021 - academic.oup.com
This clinical practice guideline for the diagnosis and treatment of acute hematogenous
osteomyelitis (AHO) in children was developed by a multidisciplinary panel representing …

Bloodstream infections in critically ill patients: an expert statement

JF Timsit, E Ruppé, F Barbier, A Tabah… - Intensive care medicine, 2020 - Springer
Bloodstream infection (BSI) is defined by positive blood cultures in a patient with systemic
signs of infection and may be either secondary to a documented source or primary—that is …

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

L Evans, A Rhodes, W Alhazzani, M Antonelli… - Critical care …, 2021 - journals.lww.com
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

SL Weiss, MJ Peters, W Alhazzani, MSD Agus… - Intensive care …, 2020 - Springer
Objectives To develop evidence-based recommendations for clinicians caring for children
(including infants, school-aged children, and adolescents) with septic shock and other …

Initial antimicrobial management of sepsis

MS Niederman, RM Baron, L Bouadma, T Calandra… - Critical care, 2021 - Springer
Sepsis is a common consequence of infection, associated with a mortality rate> 25%.
Although community-acquired sepsis is more common, hospital-acquired infection is more …

Rationalizing antimicrobial therapy in the ICU: a narrative review

JF Timsit, M Bassetti, O Cremer, G Daikos… - Intensive care …, 2019 - Springer
The massive consumption of antibiotics in the ICU is responsible for substantial ecological
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …

Infectious Diseases Society of America position paper: recommended revisions to the national severe sepsis and septic shock early management bundle (SEP-1) …

C Rhee, K Chiotos, SE Cosgrove… - Clinical Infectious …, 2021 - academic.oup.com
Abstract The Centers for Medicare & Medicaid Services' Severe Sepsis and Septic Shock
Early Management Bundle (SEP-1) measure has appropriately established sepsis as a …

[HTML][HTML] Management of KPC-producing Klebsiella pneumoniae infections

M Bassetti, DR Giacobbe, H Giamarellou… - Clinical Microbiology …, 2018 - Elsevier
Background Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-
KP) has become one of the most important contemporary pathogens, especially in endemic …

Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis

G De Pascale, M Antonelli, M Deschepper… - Intensive care …, 2022 - Springer
Purpose To describe data on epidemiology, microbiology, clinical characteristics and
outcome of adult patients admitted in the intensive care unit (ICU) with secondary peritonitis …

Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action

World Journal of Emergency Surgery, 2023 - Springer
Antibiotics are recognized widely for their benefits when used appropriately. However, they
are often used inappropriately despite the importance of responsible use within good clinical …