MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

There is an urgent need to identify novel therapies for childhood cancers. Neuroblastoma is
the most common pediatric solid tumor, and accounts for~ 15% of childhood cancer‐related …

MYCN is a member of the MYC family of proto-oncogenes. It encodes a transcription factor,
MYCN, involved in the control of fundamental processes during embryonal development …

Despite advances in the molecular exploration of paediatric cancers, approximately 50% of
children with high-risk neuroblastoma lack effective treatment. To identify therapeutic options …

Neuroblastoma (NB) is a remarkably heterogenic childhood tumor of the sympathetic
nervous system with clinical behavior ranging from spontaneous regression to poorly …

Neuroblastoma is the most common extracranical tumor of childhood and the most deadly
tumor of infancy. It is characterized by early age onset and high frequencies of metastatic …

In pediatric neuroblastoma, MYCN-amplification correlates to poor clinical outcome and new
treatment options are needed for these patients. Identifying the metabolic adaptations crucial …

The fundamental function of ribonucleic acids is to transfer genetic information from DNA to
protein during translation process, however, this is not the only way connecting active RNA …

Neuroblastoma is the most common extra-cranial solid tumor encountered in childhood and
accounts for 15% of pediatric cancer-related deaths. Although there has been significant …

Background Neuroblastoma (NB), a childhood tumor derived from the sympathetic nervous
system, presents with heterogeneous clinical behavior. While some tumors regress …