Vulvovaginal candidiasis: Epidemiology, microbiology and risk factors

B Gonçalves, C Ferreira, CT Alves… - Critical reviews in …, 2016 - Taylor & Francis
Vulvovaginal candidiasis (VVC) is an infection caused by Candida species that affects
millions of women every year. Although Candida albicans is the main cause of VVC, the …

Candida Infections of the Genitourinary Tract

JM Achkar, BC Fries - Clinical microbiology reviews, 2010 - Am Soc Microbiol
All humans are colonized with Candida species, mostly Candida albicans, yet some develop
diseases due to Candida, among which genitourinary manifestations are extremely …

Vulvovaginal Candida albicans infections: pathogenesis, immunity and vaccine prospects

A Cassone - BJOG: An International Journal of Obstetrics & …, 2015 - Wiley Online Library
Although a number of fungal species belonging to the genus C andida can cause acute
vulvovaginal infection (VVC), C andida albicans is by far the most prevalent etiological …

A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis

L Jin, X Bai, N Luan, H Yao, Z Zhang… - Journal of medicinal …, 2016 - ACS Publications
New therapeutic agents for Candida albicans vaginitis are urgently awaiting to be
developed because of the increasing antibiotic resistance of C. albicans. Antimicrobial …

[HTML][HTML] Host responses to Candida albicans: Th17 cells and mucosal candidiasis

HR Conti, SL Gaffen - Microbes and Infection, 2010 - Elsevier
Candida albicans causes mucosal and disseminated candidiasis, which represent serious
problems for the rapidly expanding immunocompromised population. Until recently, Th1 …

The Role of B-Cells and Antibodies against Candida Vaccine Antigens in Invasive Candidiasis

M Shukla, P Chandley, S Rohatgi - Vaccines, 2021 - mdpi.com
Systemic candidiasis is an invasive fungal infection caused by members of the genus
Candida. The recent emergence of antifungal drug resistance and increased incidences of …

Animal models of mucosal Candida infection

JR Naglik, PL Fidel Jr, FC Odds - FEMS microbiology letters, 2008 - academic.oup.com
Rodent models of oral, vaginal and gastrointestinal Candida infection are described and
discussed in terms of their scientific merits. The common feature of all experimental mucosal …

IL-22 and IDO1 affect immunity and tolerance to murine and human vaginal candidiasis

A De Luca, A Carvalho, C Cunha, RG Iannitti… - PLoS …, 2013 - journals.plos.org
The ability to tolerate Candida albicans, a human commensal of the gastrointestinal tract
and vagina, implicates that host defense mechanisms of resistance and tolerance cooperate …

Secreted aspartic proteases of Candida albicans activate the NLRP3 inflammasome

D Pietrella, N Pandey, E Gabrielli… - European journal of …, 2013 - Wiley Online Library
In a recent report, we demonstrated that distinct members of the secreted aspartic protease
(S ap) family of C andida albicans are able to induce secretion of proinflammatory cytokines …

A virosomal vaccine against candidal vaginitis: immunogenicity, efficacy and safety profile in animal models

F De Bernardis, M Amacker, S Arancia, S Sandini… - Vaccine, 2012 - Elsevier
A novel vaccine (PEV7) consisting of a truncated, recombinant aspartyl proteinase-2 of
Candida albicans incorporated into influenza virosomes was studied. This vaccine …