Trypanosoma cruzi, the agent of Chagas disease (ChD), exhibits remarkable biological and
genetic diversity, along with eco-epidemiological complexity. In order to facilitate …

Chagas disease is a neglected tropical disease caused by the protozoan parasite
Trypanosoma cruzi. There is an urgent need for safe, effective, and accessible new …

Trypanosomes are eukaryotic, unicellular parasites, such as Trypanosoma brucei, which
causes sleeping sickness, and Trypanosoma cruzi, which causes Chagas disease …

The protozoan Trypanosoma cruzi almost invariably establishes life-long infections in
humans and other mammals, despite the development of potent host immune responses …

AlphaFold2 and RoseTTAfold represent a transformative advance for predicting protein
structure. They are able to make very high-quality predictions given a high-quality alignment …

Chagas disease caused by the parasite Trypanosoma cruzi affects millions of people.
Although its first genome dates from 2005, its complexity hindered a complete assembly and …

The improvement and decreasing costs of third‐generation sequencing technologies has
widened the scope of biological questions researchers can address with de novo genome …

Cryptosporidiosis is a leading cause of waterborne diarrheal disease globally and an
important contributor to mortality in infants and the immunosuppressed. Despite its …

Trypanosoma cruzi, the protozoan causative of Chagas disease (ChD), exhibits striking
genetic and phenotypic intraspecific diversity, along with ecoepidemiological complexity …

Chagas disease, caused by the protozoan Trypanosoma cruzi, is a serious chronic parasitic
disease, currently treated with Nifurtimox (NFX) and Benznidazole (BZ). In addition to high …