Epstein-Barr virus (EBV) is a gammaherpesvirus that infects a large fraction of the human
population. Primary infection is often asymptomatic but results in lifelong infection, which is …

Highlights•We summarize and update the germinal center model of Epstein–Barr virus
persistence.•We discuss the weaknesses and strengths of alternate models.•The role of …

Agent-based models have been employed to describe numerous processes in immunology.
Simulations based on these types of models have been used to enhance our understanding …

Advances in a variety of computing fields, including “big data,” machine learning,
visualization, and augmented/mixed/virtual reality, have combined to give rise to the …

Cytomegalovirus (CMV) is acquired by the oral route in children, and primary infection is
associated with abundant mucosal replication, as well as the establishment of latency in …

In this study we show that in long-term persistent infection, Epstein-Barr virus (EBV)-infected
cells undergoing a germinal center (GC) reaction in the tonsils are limited to the follicles and …

Background This study aimed to assess the host immune signatures associated with EBV
infection and its clinical value in indicating the severity of children with acute infectious …

Managing the layout of multi-dimensional visualizations is a crucial concern for the
development of effective visual analytic interfaces. In these environments, heterogeneous …

Cytomegalovirus (CMV) infection occurs frequently in young children, who, when infected,
are then a major source of transmission. Oral CMV shedding by 14 infants with primary …

The really interesting thing about herpesviruses is that they can establish lifelong persistant
infections in immunocompetent hosts. At first glance, they would seem to have very different …