Mpox and HIV—Collision of Two Diseases
Abstract Purpose of Review The global outbreak of mpox has brought renewed attention to a
previously neglected disease which is particularly severe in people with underlying …
previously neglected disease which is particularly severe in people with underlying …
Antivirals against monkeypox (Mpox) in humans: an updated narrative review
G Bruno, GB Buccoliero - Life, 2023 - mdpi.com
As of 29 August 2023, a total of 89,596 confirmed cases of Mpox (monkeypox) have been
documented across 114 countries worldwide, with 157 reported fatalities. The Mpox …
documented across 114 countries worldwide, with 157 reported fatalities. The Mpox …
Mpox virus infection and drug treatment modelled in human skin organoids
Mpox virus (MPXV) primarily infects human skin to cause lesions. Currently, robust models
that recapitulate skin infection by MPXV are lacking. Here we demonstrate that human …
that recapitulate skin infection by MPXV are lacking. Here we demonstrate that human …
Tecovirimat use under expanded access to treat Mpox in the United States, 2022–2023
PA Yu, R Elmor, K Muhammad, YC Yu… - NEJM …, 2024 - evidence.nejm.org
Background During the ongoing outbreak of clade II monkeypox virus (MPXV), many US
patients were prescribed tecovirimat, an antiviral drug that was made available under an …
patients were prescribed tecovirimat, an antiviral drug that was made available under an …
[HTML][HTML] Efficacy and viral dynamics of tecovirimat in patients with MPOX: A multicenter open-label, double-arm trial in Japan
Y Akiyama, S Morioka, S Tsuzuki, T Yoshikawa… - Journal of Infection and …, 2024 - Elsevier
Introduction Tecovirimat's application in treating mpox remains under-researched, leaving
gaps in clinical and virological understanding. Methods The Tecopox study in Japan …
gaps in clinical and virological understanding. Methods The Tecopox study in Japan …
Development and Pilot of an Mpox Severity Scoring System
Clinical severity scores facilitate comparisons to understand risk factors for severe illness.
For the 2022 multinational monkeypox clade IIb virus outbreak, we developed a 7-item Mpox …
For the 2022 multinational monkeypox clade IIb virus outbreak, we developed a 7-item Mpox …
Human mpox in people living with HIV: epidemiologic and clinical perspectives from Nigeria
Sub-Saharan Africa (SSA) is disproportionately affected by mpox and HIV. We described
epidemiologic trends and clinical experiences in the management of mpox in people living …
epidemiologic trends and clinical experiences in the management of mpox in people living …
Mpox (Monkeypox) Virus and Its Co-infection with HIV, sexually transmitted infections, or bacterial superinfections: Double whammy or a new prime culprit?
Epidemiologic studies have established that mpox (formerly known as monkeypox)
outbreaks worldwide in 2022–2023, due to Clade IIb mpox virus (MPXV), disproportionately …
outbreaks worldwide in 2022–2023, due to Clade IIb mpox virus (MPXV), disproportionately …
Risk factors for hospitalization and effect of immunosuppression on clinical outcomes among an urban cohort of patients with Mpox
Background During the 2022 mpox outbreak most patients were managed as outpatients,
but some required hospitalization. Uncontrolled human immunodeficiency virus (HIV) has …
but some required hospitalization. Uncontrolled human immunodeficiency virus (HIV) has …
Therapeutic agents for the treatment of human mpox
M Braddick, KP Singh - Current Opinion in Infectious Diseases, 2024 - journals.lww.com
The 2022 multicountry outbreak of mpox marked a public health emergency. Agents
approved for smallpox management were widely used for mpox, supported by animal and in …
approved for smallpox management were widely used for mpox, supported by animal and in …