Hello from the other side: Membrane contact of lipid droplets with other organelles and subsequent functional implications

R Rakotonirina-Ricquebourg, V Costa… - Progress in Lipid …, 2022 - Elsevier
Lipid droplets (LDs) are ubiquitous organelles that play crucial roles in response to
physiological and environmental cues. The identification of several neutral lipid synthesizing …

Crucial aspects of metabolism and cell biology relating to industrial production and processing of Saccharomyces biomass

PV Attfield - Critical Reviews in Biotechnology, 2023 - Taylor & Francis
The multitude of applications to which Saccharomyces spp. are put makes these yeasts the
most prolific of industrial microorganisms. This review considers biological aspects …

Cytosolic pH controls fungal MAPK signaling and pathogenicity

TR Fernandes, M Mariscal, A Serrano, D Segorbe… - Mbio, 2023 - Am Soc Microbiol
Mitogen-activated protein kinases (MAPKs) regulate a variety of cellular processes in
eukaryotes. In fungal pathogens, conserved MAPK pathways control key virulence functions …

JAZF1: A metabolic actor subunit of the NuA4/TIP60 chromatin modifying complex

A Mameri, J Côté - Frontiers in cell and developmental biology, 2023 - frontiersin.org
The multisubunit NuA4/TIP60 complex is a lysine acetyltransferase, chromatin modifying
factor and gene co-activator involved in diverse biological processes. The past decade has …

[HTML][HTML] Vacuolar ATPase-mediated regulation of neutral lipid dynamics: Insights into lipid droplet homeostasis and stress response mechanisms

V Costa, V Teixeira - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2024 - Elsevier
This study explores the intricate relationship between the yeast vacuolar H+-ATPase (V-
ATPase) and neutral lipid metabolism. We show that LD generation observed upon loss of V …

The Plasma Membrane H+ ATPase CsPMA2 Regulates Lipid Droplet Formation, Appressorial Development and Virulence in Colletotrichum siamense

Y Liu, Y Xi, Y Lv, J Yan, M Song, H Yang… - International Journal of …, 2023 - mdpi.com
Plasma membrane H+-ATPases (PMAs) play an important role in the pathogenicity of
pathogenic fungi. Lipid droplets are important storage sites for neutral lipids in fungal …

GATA-type transcriptional factor SpGAT1 interacts with SpMIG1 and promotes lipid accumulation in the oleaginous yeast zwy-2-3

Y Ran, H Xu, Q Yang, Y Xu, H Yang, D Qiao… - … for Biofuels and …, 2022 - Springer
Background In oleaginous yeast, nitrogen limitation is a critical parameter for lipid synthesis.
GATA-family transcriptional factor GAT1, a member of the target of rapamycin (TOR) …

Yeast Cell Signaling Pathways (Volume 1)

V Teixeira - International journal of molecular sciences, 2023 - mdpi.com
This Special Issue was devoted to unravelling novel aspects of yeast biology and signal
transduction in numerous yet intricate basic processes. The work presented herein sheds …

N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis

MO Ribeiro, M Oliveira, V Nogueira, V Costa… - 2024 - researchsquare.com
Background Seipin is a protein encoded by the BSCL2 gene in humans and SEI1 gene in
yeast, forming an Endoplasmic Reticulum (ER)-bound homo-oligomer. This oligomer is …

Single-cell analysis of TORC1 and PKA signalling during the budding yeast cell cycle: towards a holistic view of growth and division

P Guerra - 2022 - research.rug.nl
Cell growth, characterized by the accumulation of biomass, and the cell division process, are
fundamental for cell survival and reproduction. Classically, it was thought that cell growth …