[HTML][HTML] Mechanisms underlying sonoporation: Interaction between microbubbles and cells

Y Yang, Q Li, X Guo, J Tu, D Zhang - Ultrasonics Sonochemistry, 2020 - Elsevier
The past several decades have witnessed great progress in “smart drug delivery”, an
advance technology that can deliver genes or drugs into specific locations of patients' body …

[HTML][HTML] Ultrasound-mediated drug delivery: sonoporation mechanisms, biophysics, and critical factors

CH YuAlfred - BME frontiers, 2022 - spj.science.org
Sonoporation, or the use of ultrasound in the presence of cavitation nuclei to induce plasma
membrane perforation, is well considered as an emerging physical approach to facilitate the …

Mechanistic understanding the bioeffects of ultrasound-driven microbubbles to enhance macromolecule delivery

P Qin, T Han, CH Alfred, L Xu - Journal of controlled release, 2018 - Elsevier
Ultrasound-driven microbubbles can trigger reversible membrane perforation
(sonoporation), open interendothelial junctions and stimulate endocytosis, thereby providing …

Mechanisms of microbubble-facilitated sonoporation for drug and gene delivery

Z Fan, RE Kumon, CX Deng - Therapeutic delivery, 2014 - Taylor & Francis
Due to the high compressibility of the gas core compared with the surrounding liquid
medium, microbubbles are highly responsive to ultrasound excitation and exhibit robust …

Microbubble-mediated ultrasound therapy: a review of its potential in cancer treatment

S Ibsen, CE Schutt, S Esener - Drug design, development and …, 2013 - Taylor & Francis
The inherently toxic nature of chemotherapy drugs is essential for them to kill cancer cells
but is also the source of the detrimental side effects experienced by patients. One strategy to …

[HTML][HTML] Sonoporation by single-shot pulsed ultrasound with microbubbles adjacent to cells

N Kudo, K Okada, K Yamamoto - Biophysical journal, 2009 - cell.com
In this article, membrane perforation of endothelial cells with attached microbubbles caused
by exposure to single-shot short pulsed ultrasound is described, and the mechanisms of …

Intracellular delivery and calcium transients generated in sonoporation facilitated by microbubbles

Z Fan, RE Kumon, J Park, CX Deng - Journal of Controlled Release, 2010 - Elsevier
Ultrasound application in the presence of microbubbles is a promising strategy for
intracellular drug and gene delivery, but it may also trigger other cellular responses. This …

Acoustic microcannons: toward advanced microballistics

F Soto, A Martin, S Ibsen, M Vaidyanathan… - ACS …, 2016 - ACS Publications
Acoustically triggered microcannons, capable of loading and firing nanobullets (Nbs), are
presented as powerful microballistic tools. Hollow conically shaped microcannon structures …

Sonoporation of suspension cells with a single cavitation bubble in a microfluidic confinement

S Le Gac, E Zwaan, A Van Den Berg, CD Ohl - Lab on a Chip, 2007 - pubs.rsc.org
We report here the sonoporation of HL60 (human promyelocytic leukemia) suspension cells
in a microfluidic confinement using a single laser-induced cavitation bubble. Cavitation …

[HTML][HTML] Development of exosome membrane materials-fused microbubbles for enhanced stability and efficient drug delivery of ultrasound contrast agent

Y Jang, J Park, P Kim, EJ Park, H Sun, Y Baek… - … Pharmaceutica Sinica B, 2023 - Elsevier
Lipid-coated microbubbles are widely used as an ultrasound contrast agent, as well as drug
delivery carriers. However, the two main limitations in ultrasound diagnosis and drug …