Early life stress (ELS), such as abuse and neglect during childhood, can lead to psychiatric
disorders in later life. Previous studies have suggested that ELS can cause profound …

Post-traumatic stress disorder (PTSD), characterized by abnormally persistent and
distressing memories, is a chronic debilitating condition in need of new treatment options …

Post-traumatic stress disorder (PTSD) is usually considered a psychiatric disorder upon
emotional trauma. However, with the rising number of conflicts and traffic accidents around …

Exosomes are extracellular vesicles with diameters of about 100 nm that are naturally
secreted by cells into body fluids. They are derived from endosomes and are wrapped in …

To transfer toxicological findings from model systems, eg animals, to humans, standardized
safety factors are applied to account for intra-species and inter-species variabilities. An …

Post-traumatic stress disorder (PTSD) is a psychopathological condition with a
heterogeneous clinical picture that is complex and challenging to treat. Its multifaceted …

Translational bioinformatics and data science play a crucial role in biomarker discovery as it
enables translational research and helps to bridge the gap between the bench research and …

Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells
with the ability to communicate with other tissues and cell types over long distances. Their …

Using a model of combat and operational stress reaction (COSR), our lab recently showed
that exposure to an unpredictable combat stress (UPCS) procedure prior to a thermal injury …

Background: Evidence suggests that memory storage is dynamic. Long-term consolidated
memories are updated with new significant experience. Retrieval of memory reactivates the …