Nasopharyngeal carcinoma: an evolving paradigm

KCW Wong, EP Hui, KW Lo, WKJ Lam… - Nature reviews Clinical …, 2021 - nature.com
The past three decades have borne witness to many advances in the understanding of the
molecular biology and treatment of nasopharyngeal carcinoma (NPC), an Epstein–Barr virus …

[HTML][HTML] Clinical trial data of Anti–PD-1/PD-L1 therapy for recurrent or metastatic nasopharyngeal Carcinoma: A review

DR Adkins, RI Haddad - Cancer Treatment Reviews, 2022 - Elsevier
Importance Anti–programmed cell death receptor-1 (PD-1) therapy is standard of care for
incurable recurrent or metastatic non-nasopharyngeal head and neck cancer. In contrast …

[HTML][HTML] Precision medicine in nasopharyngeal carcinoma: comprehensive review of past, present, and future prospect

PY Siak, WS Heng, SSH Teoh, YY Lwin… - Journal of Translational …, 2023 - Springer
Nasopharyngeal carcinoma (NPC) is an aggressive malignancy with high propensity for
lymphatic spread and distant metastasis. It is prominent as an endemic malignancy in …

[HTML][HTML] Immunotherapy in recurrent/metastatic squamous cell carcinoma of the head and neck

RW Hsieh, S Borson, A Tsagianni… - Frontiers in oncology, 2021 - frontiersin.org
Head and neck cancer is the 6th most common cancer worldwide with the most common
histology being squamous cell carcinoma (HNSCC). While the majority of patients present at …

[HTML][HTML] Impact of epstein barr virus infection on treatment opportunities in patients with nasopharyngeal cancer

F Perri, F Sabbatino, A Ottaiano, R Fusco, M Caraglia… - Cancers, 2023 - mdpi.com
Simple Summary Epstein Barr virus (EBV) is often responsible for the onset of both solid and
hematologic malignancies. In particular, it is implicated in the pathogenesis of …

[HTML][HTML] Pharmacological, technological, and digital innovative aspects in rhinology

R Ruggiero, G Motta, G Massaro, C Rafaniello… - Frontiers in …, 2021 - frontiersin.org
Innovation refers to the introduction of a product, a process, a service or a solution resulting
in something new or significantly improved compared to the already available alternatives …

Advances in pharmacotherapy for head and neck cancer

S Kumar, V Noronha, V Patil, A Joshi… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction: Head and neck squamous cell carcinoma (HNSCC) is one of the most common
cancers worldwide and is a leading cause for cancer-related mortality. This review attempts …

Targeted Therapy and Immunotherapy for Nasopharyngeal Carcinoma

BBY Ma, EP Hui, ATC Chan - 2023 - Springer
The mutational landscape of NPC has been elucidated by several whole-exome (WES) and
whole-genome (WGS) sequencing studies of NPC published since 2014 (Dai et al. 2020; Li …

Immunotherapy in Recurrent and Metastatic Nasopharyngeal Carcinoma

BBY Ma, ATC Chan - Immunotherapy for Head and Neck Cancer, 2022 - Springer
The last 5 years have borne witness to a major revival in the use of immunotherapy against
nasopharyngeal cancer (NPC), a milestone that is due largely to the successful …

Systemic Therapy in Recurrent or Metastatic Squamous Cell Head and Neck Cancer

I Kiladze, G ÖZYİĞİT, P Dubinsky… - TURK ONKOLOJI …, 2021 - avesis.hacettepe.edu.tr
Squamous cell head and neck cancer (SCHNC) is the seventh most common cancer
worldwide. Most of SCHNC are locally advanced at diagnosis and are treated with …