The causal relationship between endothelin-1 and hypertension: focusing on endothelial dysfunction, arterial stiffness, vascular remodeling, and blood pressure …
K Kostov - Life, 2021 - mdpi.com
Hypertension (HTN) is one of the most prevalent diseases worldwide and is among the most
important risk factors for cardiovascular and cerebrovascular complications. It is currently …
important risk factors for cardiovascular and cerebrovascular complications. It is currently …
Role of magnesium deficiency in promoting atherosclerosis, endothelial dysfunction, and arterial stiffening as risk factors for hypertension
K Kostov, L Halacheva - International journal of molecular sciences, 2018 - mdpi.com
Arterial hypertension is a disease with a complex pathogenesis. Despite considerable
knowledge about this socially significant disease, the role of magnesium deficiency (MgD) …
knowledge about this socially significant disease, the role of magnesium deficiency (MgD) …
A network pharmacology-based strategy for predicting active ingredients and potential targets of LiuWei DiHuang pill in treating type 2 diabetes mellitus
D He, JH Huang, ZY Zhang, Q Du… - Drug Design …, 2019 - Taylor & Francis
Background Traditional Chinese medicine (TCM) formulations have proven to be
advantageous in clinical treatment and prevention of disease. LiuWei DiHuang Pill (LWDH …
advantageous in clinical treatment and prevention of disease. LiuWei DiHuang Pill (LWDH …
Blood–brain barrier disruption and its involvement in neurodevelopmental and neurodegenerative disorders
The blood–brain barrier (BBB) is a highly specialized and dynamic compartment which
regulates the uptake of molecules and solutes from the blood. The relevance of the …
regulates the uptake of molecules and solutes from the blood. The relevance of the …
GIP affects hepatic fat and brown adipose tissue thermogenesis but not white adipose tissue transcriptome in type 1 diabetes
SMN Heimbürger, B Hoe, CN Nielsen… - The Journal of …, 2022 - academic.oup.com
Context Glucose-dependent insulinotropic polypeptide (GIP) has been proposed to exert
insulin-independent effects on lipid and bone metabolism. Objective We investigated the …
insulin-independent effects on lipid and bone metabolism. Objective We investigated the …
Pericyte contractile responses to endothelin-1 and Aβ peptides: assessment by electrical impedance assay
Pericytes are vascular mural cells that contract and relax in response to vasoactive stimuli to
regulate neurovascular coupling and cerebral blood flow. Pericytes are damaged and …
regulate neurovascular coupling and cerebral blood flow. Pericytes are damaged and …
Use of glycated hemoglobin (A1c) as a biomarker for vascular risk in type 2 diabetes: Its relationship with matrix metalloproteinases-2,-9 and the metabolism of …
Background and objectives: HbA1c measurements may be useful not only in optimizing
glycemic control but also as a tool for managing overall vascular risk in patients with …
glycemic control but also as a tool for managing overall vascular risk in patients with …
Changes in serum levels of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinases-1 in patients with essential hypertension
Hypertension (HTN) is a leading risk factor for cardiovascular (CV) disease. Matrix
metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are thought to be actively …
metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are thought to be actively …
Circulating levels of endothelin-1 and big endothelin-1 in patients with essential hypertension
The role of endothelin-1 (ET-1) in the pathogenesis of hypertension (HTN) is not clearly
established. There is evidence that its circulating levels are elevated in some forms of …
established. There is evidence that its circulating levels are elevated in some forms of …
Serum biomarkers of cardiovascular remodelling reflect extra-valvular cardiac damage in patients with severe aortic stenosis
L Bäz, G Dannberg, K Grün, J Westphal… - International journal of …, 2020 - mdpi.com
In patients with aortic stenosis (AS), a novel staging classification of extra-valvular left and
right heart damage with prognostic relevance was introduced in 2017. The aim of the study …
right heart damage with prognostic relevance was introduced in 2017. The aim of the study …