As resident component of the innate immunity in the central nervous system (CNS),
microglia are key players in pathology. However, they also exert fundamental roles in brain …

Remyelination, namely, the formation of new myelin sheaths around denuded axons,
counteracts axonal degeneration and restores neuronal function. Considerable advances …

Enhancing neurogenesis within the hippocampal dentate gyrus (DG) is critical for
maintaining brain development and function in many neurological diseases. However, the …

Depression is a neuropsychiatric disease associated with neuronal anomalies within
specific brain regions. In the present study, we screened microRNA (miRNA) expression …

Background We aimed to assess the interactions between mixed heavy metals, genes, and
miRNAs implicated in depression development and to design and create miRNA sponges …

Effective nose-to-brain delivery needs to be developed to treat neurodegenerative diseases.
Regulating miR-124 can effectively improve the symptoms of ischemic brain injury and …

In the last decade, microRNAs have been increasingly recognized as key modulators of glial
development. Recently, we identified miR‐125a‐3p as a new player in oligodendrocyte …

Dramatic advancement has been made in recent decades to understand the basis of
autoimmunity-mediated neurological diseases. These diseases create a strong influence on …

Delivery of therapeutic substances into the brain poses a significant challenge in the
treatment of neurological disorders. This is primarily due to the blood–brain barrier (BBB) …

Extracellular vesicles (EVs) have been increasingly recognized as essential players in cell
communication in many organs and systems, including the central nervous system (CNS). A …