Pathogen typing in the genomics era: MLST and the future of molecular epidemiology

M Pérez-Losada, P Cabezas, E Castro-Nallar… - Infection, Genetics and …, 2013 - Elsevier
Multi-locus sequence typing (MLST) is a high-resolution genetic typing approach to identify
species and strains of pathogens impacting human health, agriculture (animals and plants) …

Restricted gene flow among hospital subpopulations of Enterococcus faecium

RJL Willems, J Top, W van Schaik, H Leavis, M Bonten… - MBio, 2012 - Am Soc Microbiol
Enterococcus faecium has recently emerged as an important multiresistant nosocomial
pathogen. Defining population structure in this species is required to provide insight into the …

Vancomycin-resistant enterococci: Troublemaker of the 21st century

S Ranotkar, P Kumar, S Zutshi, KS Prashanth… - Journal of Global …, 2014 - Elsevier
The emergence of multidrug-resistant and vancomycin-resistant enterococci during the last
decade has made it difficult to treat nosocomial infections. Although various enterococcal …

Dispersion of the Vancomycin Resistance Genes vanA and vanC of Enterococcus Isolated from Nile Tilapia on Retail Sale: A Public Health Hazard

KM Osman, MN Ali, I Radwan, F ElHofy… - Frontiers in …, 2016 - frontiersin.org
Although normally regarded harmless commensals, enterococci may cause a range of
different infections in humans, including urinary tract infections, sepsis, and endocarditis …

Mycobacterium abscessus infection in cystic fibrosis: molecular typing and clinical outcomes

KA Harris, DTD Kenna - Journal of medical microbiology, 2014 - microbiologyresearch.org
Mycobacterium abscessus is a significant pathogen in the cystic fibrosis patient population.
PCR amplification and sequencing can provide accurate subspecies identification, and can …

Within-host evolution of Enterococcus faecium during longitudinal carriage and transition to bloodstream infection in immunocompromised patients

D Moradigaravand, T Gouliouris, B Blane… - Genome medicine, 2017 - Springer
Background Enterococcus faecium is a leading cause of hospital-acquired infection,
particularly in the immunocompromised. Here, we use whole genome sequencing of E …

Genetic Characterization of vanA-Enterococcus faecium Isolates from Wild Red-Legged Partridges in Portugal

V Silva, G Igrejas, I Carvalho, F Peixoto… - Microbial Drug …, 2018 - liebertpub.com
Vancomycin-resistant enterococci (VRE) have been detected in wild animals representing a
public health concern. The red-legged partridge (Alectoris rufa) is a common game bird and …

Determination of virulence and multidrug resistance genes with polymerase chain reaction method in vancomycin-sensitive and-resistant enterococci isolated from …

ŞS Çopur, F Şahin… - Turkish Journal of Medical …, 2016 - journals.tubitak.gov.tr
Background/aim: Enterococci play an important role in nosocomial infections. Therefore, this
study investigates multidrug resistance (MDR) 1 gene areas in the pathogenicity of …

Multilocus sequence typing of pathogens

M Pérez-Losada, ML Porter, RP Viscidi… - Genetics and Evolution of …, 2011 - Elsevier
Publisher Summary Several molecular typing methods have been proposed that can identify
isolates in localized disease outbreaks. The main standard for molecular typing is multilocus …

Changed epidemiology during intra and interhospital spread of high-risk clones of vanA-containing Enterococcus in Brazilian hospitals

AG Sacramento, RC Zanella, F Esposito… - … and Infectious Disease, 2017 - Elsevier
We report changes in the molecular epidemiology of vanA-containing Enterococcus during
the intra and interhospital spread of high-risk clones, in Southeastern Brazil. While VRE …