Mutations in the leucine-rich-repeat kinase 2 (LRRK2) gene are associated with familial and
sporadic cases of Parkinson's disease but are also found in immune-related disorders such …

Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), a leading
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …

Periodontitis is a chronic inflammatory disease associated with a dysbiotic bacterial biofilm
in the subgingival environment that may disturb the balance between the oral microbiome …

Cellular responses to stress can be defined by the overwhelming number of changes that
cells go through upon contact with and stressful conditions such as infection and …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) infection, remains a major
global health emergency. It is estimated that one third of global population are affected …

The present work aimed to review the potential mechanisms used by macrophages to kill
intracellular bacteria, their entrance to the cell, and mechanisms of escape of cellular …

Pathogenesis hallmarks for tuberculosis (TB) are the Mycobacterium tuberculosis (Mtb)
escape from phagolysosomal destruction and limited drug delivery into infected cells …

The major causative agent of tuberculosis (TB), ie, Mycobacterium tuberculosis (Mtb), has
developed mechanisms to evade host defense responses and persist within host cells for …

There is a strong relationship between metabolic state and susceptibility to Mycobacterium
tuberculosis (MTB) infection, with energy metabolism setting the basis for an exaggerated …

Despite co-evolving with humans for centuries and being intensely studied for decades, the
immune correlates of protection against Mycobacterium tuberculosis (Mtb) have yet to be …