One in three people will be diagnosed with cancer during their lifetime. The community of
cancer patients is growing, and several common cancers are becoming increasingly …

Over three decades of evidence indicate that dopamine (DA) D3 receptors (D3R) are
involved in the control of drug-seeking behavior and may play an important role in the …

Understanding the neurochemistry underlying sex differences in psychostimulant use
disorders (PSUD) is essential for developing related therapeutics. Many psychostimulants …

Dopamine (DA), the most abundant human brain catecholaminergic neurotransmitter,
modulates key behavioral and neurological processes in young and senescent brains …

Psychostimulants target the dopamine transporter (DAT) to elicit their psychomotor actions.
Bile acids (BAs) can also bind to DAT and reduce behavioral responses to cocaine …

Modafinil is a central nervous system stimulant approved for the treatment of narcolepsy and
sleep disorders. Due to its wide range of biochemical actions, modafinil has been explored …

Background This study tested an adaptive intervention for optimizing abstinence outcomes
over phases of treatment for cocaine use disorder using a SMART design. Phase 1 …

While the illicit use and misuse of stimulants like cocaine and methylphenidate (MP) has
increased, there remains no FDA‐approved treatments for psychostimulant use disorders …

Despite considerable efforts, there remains no FDA-approved medications for cocaine use
disorder (CUD). One strategy to mitigate cocaine craving and relapse is to elevate dopamine …

Evidence for acute amphetamine effects on behavioural impulsivity in healthy populations
remains elusive and, at times, mixed. This review collates and reviews the clinical literature …