The minireview surveys the modification of native nucleosides as a result of which huge
libraries of nucleoside analogs of various structures were synthesized. Particular attention is …

Antiretroviral Therapy (ART) is an effective treatment for human immunodeficiency virus
(HIV) which has transformed the highly lethal disease, acquired immunodeficiency …

Chiral phosphine-containing skeletons are important motifs in bioactive natural products,
pharmaceuticals, chiral catalysts, and ligands. Herein, we report a general and modular …

Transition‐metal‐catalyzed asymmetric carbon− carbon bond formation to forge
phosphonates with an α‐chiral carbon center through C (sp3)− C (sp3) and C (sp2)− C (sp3) …

The metabolic labeling of nucleic acids in living cells is highly desirable to track the
dynamics of nucleic acid metabolism in real‐time and has the potential to provide novel …

We report on the synthesis and evaluation of three different nucleotide prodrug systems:(i)
nucleoside triphosphate analogues in which the γ-phosph (on) ate has two different …

Transition‐metal‐catalyzed coupling reactions that involve the direct functionalization of
insert C− H bond represent one of the most efficient strategies for forming carbon‐carbon …

A series of 5′-phosphorylated (dialkyl phosphates, diaryl phosphates, phosphoramidates,
H-phosphonates, phosphates) 1, 2, 3-triazolyl nucleoside analogues in which the 1, 2, 3 …

Nucleoside analogs require three phosphorylation steps catalyzed by cellular kinases to
give their triphosphorylated metabolites. Herein, the synthesis of two types of triphosphate …

We report on the synthesis and characterization of three types of nucleoside tetraphosphate
derivatives 4–9 acting as potential prodrugs of d4T nucleotides:(i) the δ-phosph (on) ate is …