Highlights•3DP has the potential to revolutionize personalized therapy.•Rapid increase in
3PD formulations reported during past 5 years.•Potential for cost-effective production of …

Abstract Three-dimensional printing (3DP) technology is an innovative tool used in
manufacturing medical devices, producing alloys, replacing biological tissues, producing …

Pancreatic cancer (PanCa) is a major cause of cancer-related death due to limited
therapeutic options. As pancreatic tumors are highly desmoplastic, they prevent appropriate …

Background Flavonoids may help ameliorate the incidence of the major causes of tumor-
related mortality, such as pancreatic ductal adenocarcinoma (PDAC) and lung cancer, which …

Three-dimensional (3D) printing technology involves the application of digital models to
create 3D objects. It is used in construction and manufacturing and has gradually spread to …

Pancreatic cancer has a high rate of local recurrence and poor prognosis even with adjuvant
chemotherapy after curative resection. The aim of this study was to investigate if local drug …

Pancreatic cancer is a highly malignant cancer associated with high expression levels of
sonic hedgehog signaling molecule (Shh), patched 1 (Ptch1), smoothened frizzled class …

With the rapid development of three-dimensional (3D) bioprinting technology, the research
revolving around in vitro functional pancreas and tumor models has become the focus of …

Introduction: Epilepsy is a chronic brain disease characterized by unprovoked seizures,
which can have severe consequences including loss of awareness and death. Currently …

Fluorouracil (5-FU) is a “cytotoxic” drug used for cancer chemotherapy, which inhibits cells
division via affecting DNA synthesis. Although being widely used for cancer treatment, 5-FU …