A guide to 90Y radioembolization and its dosimetry

SP Kim, C Cohalan, N Kopek, SA Enger - Physica Medica, 2019 - Elsevier
Radioembolization gains continuous traction as a primarily palliative radiation treatment for
hepatic tumours. A form of nuclear medicine therapy, Yttrium-90 containing microspheres …

Transarterial radioembolization for hepatocellular carcinoma and hepatic metastases: Clinical aspects and dosimetry models

JK Mikell, YK Dewaraja, D Owen - Seminars in radiation oncology, 2020 - Elsevier
Transarterial radioembolization (TARE) with Yttrium-90 (90 Y) microspheres is a liver-
directed therapy for primary and metastatic disease. This manuscript provides a review of …

Radioembolization dosimetry with total-body 90Y PET

G Costa, B Spencer, N Omidvari, C Foster… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Transarterial radioembolization (TARE) is a locoregional radiopharmaceutical therapy
based on the delivery of radioactive 90Y microspheres to liver tumors. The importance of …

Impact of respiratory motion and acquisition settings on SPECT liver dosimetry for radioembolization

R Bastiaannet, MA Viergever… - Medical physics, 2017 - Wiley Online Library
Purpose Respiratory motion may impose significant inaccuracies on emission activity
estimation in quantitative SPECT. This effect may be a major issue in dosimetry as used in …

Precision dosimetry in yttrium-90 radioembolization through CT imaging of radiopaque microspheres in a rabbit liver model

EC Henry, M Strugari, G Mawko, K Brewer, D Liu… - EJNMMI physics, 2022 - Springer
Purpose To perform precision dosimetry in yttrium-90 radioembolization through CT imaging
of radiopaque microspheres in a rabbit liver model and to compare extracted dose metrics to …

Tumor-to-normal ratio relationship between planning Technetium-99 macroaggregated albumin and posttherapy Yttrium-90 Bremsstrahlung SPECT/CT

A Villalobos, B Cheng, W Wagstaff, I Sethi… - Journal of Vascular and …, 2021 - Elsevier
Purpose To quantify the relationship of the tumor-to-normal ratio (TNR) attained from the
technetium-99m macroaggregated albumin (MAA) and posttreatment yttrium-90 …

Pre-and post-treatment image-based dosimetry in 90Y-microsphere radioembolization using the TOPAS Monte Carlo toolkit

A Bertolet, E Wehrenberg-Klee, M Bobić… - Physics in Medicine …, 2021 - iopscience.iop.org
Objective. To evaluate the pre-treatment and post-treatment imaging-based dosimetry of
patients treated with 90Y-microspheres, including accurate estimations of dose to tumor …

Relationship of radiation dose to efficacy of radioembolization of liver metastasis from breast cancer

F Ridouani, MM Soliman, RW England, M Hsu… - European journal of …, 2021 - Elsevier
Purpose To determine the relationship of tumoral and nontumoral radiation dose to
response and toxicity after transarterial radioembolization (TARE) of breast cancer liver …

Microfluidic fabrication of silica microspheres infused with positron emission tomography imaging agents

LI Larsen, GP López, R Selwyn… - ACS Applied Bio …, 2023 - ACS Publications
Selective internal radiation therapy (SIRT) is a treatment which delivers radioactive
therapeutic microspheres via the hepatic artery to destroy tumorigenic tissue of the liver …

Development of a scatter correction technique for planar 99mTc-MAA imaging to improve accuracy in lung shunt fraction estimation

N McArdle, S Cournane, J McCavana, J Lucey… - Physica Medica, 2022 - Elsevier
Purpose Prior to 90 Y selective internal radiation therapy (SIRT) treatment, 99m Tc-MAA
scintigraphy imaging is used in the estimation of the lung shunt fraction (LSF). Planar …