Investigation of Novel Quinoline–Thiazole Derivatives as Antimicrobial Agents: In Vitro and In Silico Approaches

AE Evren, AB Karaduman, BN Saglik, Y Ozkay… - ACS …, 2022 - ACS Publications
Infectious diseases are a major concern around the world. Today, it is an urgent need for
new chemotherapeutics for infectious diseases. Because of that, our group designed …

On the formation of uncommon pyrazoloazepines from 5-aminopyrazoles as by-products in the Clauson-Kaas reaction

D Bortňák, V Milata, J Šofranko, D Végh… - Journal of Molecular …, 2018 - Elsevier
An unexpected generation of a 5, 7-bicyclic framework from 5-aminopyrazoles and 2, 5-
dimethoxytetrahydrofuran was detected in the synthesis of originally desired 5-pyrrol-1 …

Two novel potent perfluorophenylhydrazone derivatives, 1-((4-bromothiophen-2-yl) methylene)-2-(perfluorophenyl) hydrazine, and 1-((4-bromo-5-methylthiophen-2-yl …

J Sivý, D Bortňák, D Végh, E Rakovský - Acta Chimica Slovaca, 2023 - sciendo.com
Two potent novel perfluorophenylhydrazone derivatives are presented as multi-target
compounds to combat Alzheimer disease C11H4BrF5N2S, 1-((4-bromothiophen-2-yl) …

[PDF][PDF] Synthesis, crystal structure and Hirshfeld surface analysis of (4-methylphenyl)[1-(pentafluorophenyl)-5-(trifluoromethyl)-1H-1, 2, 3-triazol-4-yl] methanone

NT Pokhodylo, Y Slyvka, E Goreshnik… - Acta Crystallographica …, 2021 - journals.iucr.org
The title compound, C17H7F8N3O, was obtained via the reaction of 1-azido-2, 3, 4, 5, 6-
pentafluorobenzene with 4, 4, 4-trifluoro-1-(p-tolyl) butane-1, 3-dione using triethylamine as …

Mass spectrometrical and quantum‐chemical study of pentafluorophenylhydrazones

D Bortňák, D Pecher, D Végh, M Breza… - Journal of Mass …, 2020 - Wiley Online Library
Twenty‐one pentafluorphenylhydrazones have been analyzed by means of tandem mass
spectrometry (ESI MS/MS) conditions to compare their fragmentations with those ones …

Bazı Yeni Kinolin Türevlerinin Sentezi, Antimikrobiyal Ve Dna Giraz Inhibitörü Etkilerinin Araştırılmas

AE Evren - 2019 - search.proquest.com
Enfeksiyon, bir organizmada patojen mikroorganizmaların neden olduğu birtakım
istenmeyen etkilerin görülmesine denir. Özellikle de bakteri ve mantar kaynaklı …

Unexpected Cleavage of N‐N Bonds of Pentafluorophenylhydrazones–Formation of Nitriles by a Radical Fragmentation Reaction

D Bortňák, V Milata, J Šofranko, D Végh… - …, 2020 - Wiley Online Library
A novel method of the preparation of (hetero) aryl nitriles based on the fragmentation of the
corresponding pentafluorophenylhydrazones is described. The synthesis is metal‐free …

Two compounds of 1-((4-bromothiophen-2-yl) methylene)-2-(perfluorophenyl) hydrazine, and 1-((4-bromo-5-methylthiophen-2-yl) methylene)-2-(perfluorophenyl) …

J Sivý, D Bortňák, D Végh, E Rakovský - 2021 - preprints.org
Abstract The crystals, C11H4BrF5N2S,(I), 1-((4-bromothiophen-2-yl) methylene)-2-
(perfluorophenyl) hydrazine and C12H6BrF5N2S,(II), 1-((4-bromo-5-methylthiophen-2-yl) …

[PDF][PDF] FRONC Marek (SK), SIVÝ Július (SK), BORTŇÁK Dušan (SK)

VD SK, KM SK - evlm.stuba.sk
The pentafluorophenyl group is an important constituent not only in biological chemistry, but
also in analytical, material and polymer chemistry, catalysis, dynamic combinatorial …