With an estimated 9.4 million new cases globally, tuberculosis (TB) continues to be a major
public health concern. Eighty percent of all cases worldwide occur in 22 high-burden, mainly …

Tuberculosis of the central nervous system (CNS) is a highly devastating form of
tuberculosis, which, even in the setting of appropriate antitubercular therapy, leads to …

Tuberculosis is transmitted from person to person by respiratory droplets. Although some
people develop active tuberculosis disease after infection, almost all tuberculosis infections …

The diagnosis of tuberculous meningitis (TBM) is difficult and poses a significant challenge
to physicians worldwide. Recently, nucleic acid amplification (NAA) tests have shown …

Molecular diagnostics in tuberculosis has enabled rapid detection of Mycobacterium
tuberculosis complex in clinical specimens, identification of mycobacterial species, detection …

T uberculosis (TB) remains a leading cause of mortality in children worldwide. The diagnosis
of tuberculosis in children is traditionally based on exposure history, symptoms, the …

Although a disease of humankind since the dawn of creation, tuberculosis remains a
scourge of modern humans. Tuberculosis (TB), or phthisis (consumption), as it was called …

Although nucleic acid amplification tests (NAATs) promise a rapid, definitive diagnosis of
tuberculous meningitis, the performance of first-generation NAATs was suboptimal and …

Nucleic acid amplification techniques (NAATs) have been demonstrated to make significant
improvements in the diagnosis of tuberculosis (TB), particularly in the time to diagnosis and …

The paucibacillary nature of the cerebrospinal fluid (CSF) has been a major obstacle in the
diagnosis of human tuberculous meningitis (TBM). This study shows that with molecular …