Glial contributions to neurodegeneration in tauopathies
CEG Leyns, DM Holtzman - Molecular neurodegeneration, 2017 - Springer
Tauopathies are a broad set of neurodegenerative dementias characterized by aggregation
of the tau protein into filamentous inclusions that can be found in neurons and glial cells …
of the tau protein into filamentous inclusions that can be found in neurons and glial cells …
Melatonin and autophagy in aging-related neurodegenerative diseases
F Luo, AF Sandhu, W Rungratanawanich… - International Journal of …, 2020 - mdpi.com
With aging, the nervous system gradually undergoes degeneration. Increased oxidative
stress, endoplasmic reticulum stress, mitochondrial dysfunction, and cell death are …
stress, endoplasmic reticulum stress, mitochondrial dysfunction, and cell death are …
Important role of microglia in HIV-1 associated neurocognitive disorders and the molecular pathways implicated in its pathogenesis
The development of effective combined anti-retroviral therapy (cART) led to a significant
reduction in the death rate associated with human immunodeficiency virus type 1 (HIV-1) …
reduction in the death rate associated with human immunodeficiency virus type 1 (HIV-1) …
HIV neuroinfection and Alzheimer's disease: similarities and potential links?
Environmental factors such as chemicals, stress and pathogens are now widely believed to
play important roles in the onset of some brain diseases, as they are associated with …
play important roles in the onset of some brain diseases, as they are associated with …
Ellagic acid prevents binge alcohol-induced leaky gut and liver injury through inhibiting gut dysbiosis and oxidative stress
D Kim, Y Sim, J Hwang, IS Kwun, JH Lim, J Kim, JI Kim… - Antioxidants, 2021 - mdpi.com
Alcoholic liver disease (ALD) is a major liver disease worldwide and can range from simple
steatosis or inflammation to fibrosis/cirrhosis, possibly through leaky gut and systemic …
steatosis or inflammation to fibrosis/cirrhosis, possibly through leaky gut and systemic …
[HTML][HTML] Pomegranate prevents binge alcohol-induced gut leakiness and hepatic inflammation by suppressing oxidative and nitrative stress
Alcoholic liver disease (ALD) is a major chronic liver disease worldwide and can range from
simple steatosis, inflammation to fibrosis/cirrhosis possibly through leaky gut and systemic …
simple steatosis, inflammation to fibrosis/cirrhosis possibly through leaky gut and systemic …
Apoptosis of enterocytes and nitration of junctional complex proteins promote alcohol-induced gut leakiness and liver injury
Background & Aims Binge alcohol exposure causes gut leakiness, contributing to increased
endotoxemia and inflammatory liver injury, although the molecular mechanisms are still …
endotoxemia and inflammatory liver injury, although the molecular mechanisms are still …
CCR5 antagonist reduces HIV-induced amyloidogenesis, tau pathology, neurodegeneration, and blood-brain barrier alterations in HIV-infected hu-PBL-NSG mice
B Bhargavan, SM Woollard, JE McMillan… - Molecular …, 2021 - Springer
Background Neurocognitive impairment is present in 50% of HIV-infected individuals and is
often associated with Alzheimer's Disease (AD)-like brain pathologies, including increased …
often associated with Alzheimer's Disease (AD)-like brain pathologies, including increased …
Global m6A methylation and gene expression patterns in human microglial HMC3 cells infected with HIV-1
Q Peng, J Qiao, W Li, Q You, S Hu, Y Liu, W Liu, K Hu… - Heliyon, 2023 - cell.com
Abstract N6-methyladenosine (m6A) methylation of human immunodeficiency virus type 1
(HIV-1) RNA regulates viral replication, and the m6A of host RNA is affected by HIV-1 …
(HIV-1) RNA regulates viral replication, and the m6A of host RNA is affected by HIV-1 …
Risk factors and pathogenesis of HIV-associated neurocognitive disorder: the role of host genetics
IS Olivier, R Cacabelos, V Naidoo - International journal of molecular …, 2018 - mdpi.com
Neurocognitive impairments associated with human immunodeficiency virus (HIV) infection
remain a considerable health issue for almost half the people living with HIV, despite …
remain a considerable health issue for almost half the people living with HIV, despite …