[HTML][HTML] High density lipoproteins and oxidative stress in breast cancer
G Mazzuferi, T Bacchetti, MO Islam… - Lipids in Health and …, 2021 - Springer
Breast cancer is one of the main leading causes of women death. In recent years, attention
has been focused on the role of lipoproteins, alterations of cholesterol metabolism and …
has been focused on the role of lipoproteins, alterations of cholesterol metabolism and …
[HTML][HTML] Multifaced roles of HDL in sepsis and SARS-CoV-2 infection: Renal implications
High-density lipoproteins (HDLs) are a class of blood particles, principally involved in
mediating reverse cholesterol transport from peripheral tissue to liver. Omics approaches …
mediating reverse cholesterol transport from peripheral tissue to liver. Omics approaches …
[HTML][HTML] Beneficial effects of recombinant CER-001 high-density lipoprotein infusion in sepsis: results from a bench to bedside translational research project
Background Sepsis is characterized by a dysregulated immune response and metabolic
alterations, including decreased high-density lipoprotein cholesterol (HDL-C) levels. HDL …
alterations, including decreased high-density lipoprotein cholesterol (HDL-C) levels. HDL …
Potent anti‐inflammatory properties of HDL in vascular smooth muscle cells mediated by HDL‐S1P and their impairment in coronary artery disease due to lower HDL …
P Keul, A Polzin, K Kaiser, M Gräler… - The FASEB …, 2019 - Wiley Online Library
Dysfunctional HDL is associated with coronary artery disease (CAD), but its effect on
inflammation in vascular smooth muscle cells (VSMCs) in atherosclerosis is unknown. We …
inflammation in vascular smooth muscle cells (VSMCs) in atherosclerosis is unknown. We …
[HTML][HTML] Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages
M Vaidya, JA Jentsch, S Peters, P Keul, S Weske… - Journal of Lipid …, 2019 - ASBMB
Sphingolipid and cholesterol metabolism are closely associated at the structural,
biochemical, and functional levels. Although HDL-associated sphingosine-1-phosphate …
biochemical, and functional levels. Although HDL-associated sphingosine-1-phosphate …
[HTML][HTML] HDL function across the lifespan: from childhood, to pregnancy, to old age
The function of high-density lipoprotein (HDL) particles has emerged as a promising
therapeutic target and the measurement of HDL function is a promising diagnostic across …
therapeutic target and the measurement of HDL function is a promising diagnostic across …
[HTML][HTML] Effective treatment of diabetic cardiomyopathy and heart failure with reconstituted HDL (Milano) in mice
The risk of heart failure (HF) is prominently increased in patients with type 2 diabetes
mellitus. The objectives of this study were to establish a murine model of diabetic …
mellitus. The objectives of this study were to establish a murine model of diabetic …
[HTML][HTML] Selective HDL-raising human Apo AI gene therapy counteracts cardiac hypertrophy, reduces myocardial fibrosis, and improves cardiac function in mice with …
Epidemiological studies support an independent inverse association between high-density
lipoprotein (HDL) cholesterol levels and heart failure incidence. The effect of selective HDL …
lipoprotein (HDL) cholesterol levels and heart failure incidence. The effect of selective HDL …
[HTML][HTML] Reconstituted HDL (Milano) treatment efficaciously reverses heart failure with preserved ejection fraction in mice
Heart failure with preserved ejection fraction (HFpEF) represents a major unmet therapeutic
need. This study investigated whether feeding coconut oil (CC diet) for 26 weeks in female …
need. This study investigated whether feeding coconut oil (CC diet) for 26 weeks in female …
Successful treatment of established heart failure in mice with recombinant HDL (Milano)
Background and Purpose The pleiotropic properties of HDL may exert beneficial effects on
the myocardium. The effect of recombinant HDLMilano on established heart failure was …
the myocardium. The effect of recombinant HDLMilano on established heart failure was …