Cancer metastasis is the primary cause of morbidity and mortality in cancer as it remains the
most complicated, devastating, and enigmatic aspect of cancer. Several decades of …

Approximately 30 to 40% of patients with advanced lung cancer will develop bone
metastases in the course of their disease, resulting in a significant negative impact on both …

Identification of disease-associated miRNAs (disease miRNAs) are critical for understanding
etiology and pathogenesis. Most previous methods focus on integrating similarities and …

Lung cancer is the leading cause of cancer-related death worldwide. Bone metastasis,
which usually accompanies severe skeletal-related events, is the most common site for …

Purpose To investigate the levels for some specified microRNAs in human's peripheral
blood so as to determine whether they can serve as biomarkers for metastatic non-small-cell …

Simple Summary Metastasis is a complex dynamic multistep process; however, our
knowledge is still limited. Very few circulating tumor cells (CTCs) are metastatic precursor …

Adhesion is a hallmark of haematological and solid cancer cells. All five classes of cell
adhesion molecules (CAM)-integrins, cadherins, immunoglobulin-like CAMs, selectins and …

Osteosarcoma (OS) is a highly malignant primary skeletal tumor with a striking tendency to
rapidly destroy the surrounding bone and metastasize, since metastases are frequently …

Ezrin is highly expressed in metastatic tumors and is involved in filopodia formation as well
as promotion of tumor metastasis. Thus, Ezrin may serve as a potential target for anti …

More and more studies have investigated the effects of Ezrin expression level on the
prognostic role in various tumors. However, the results remain controversial rather than …