Ferroptosis is a new type of cell death that was discovered in recent years and is usually
accompanied by a large amount of iron accumulation and lipid peroxidation during the cell …

Ferroptosis is a newly discovered form of regulated cell death that is the nexus between
metabolism, redox biology, and human health. Emerging evidence shows the potential of …

Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved cellular
process capable of degrading various biological molecules (eg, protein, glycogen, lipids …

Ferroptosis is widely involved in degenerative diseases in various tissues including kidney,
liver and brain, and is a targetable vulnerability in multiple primary and therapy-resistant …

The transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) is a key regulator of
the cellular antioxidant response, controlling the expression of genes that counteract …

One of the key challenges in cancer research is how to effectively kill cancer cells while
leaving the healthy cells intact. Cancer cells often have defects in cell death executioner …

Although cancer immunotherapy has emerged as a tremendously promising cancer therapy
method, it remains effective only for several cancers. Photoimmunotherapy (eg …

Ferroptosis is a type of iron-dependent regulated cell death, representing an emerging
disease-modulatory mechanism. Transcription factors play multiple roles in ferroptosis …

Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …

Oxidative stress-mediated retinal pigment epithelium (RPE) degeneration plays a vital role
in retinal degeneration with irreversible visual impairment, most notably in age-related …