Ferroptosis: past, present and future
J Li, F Cao, H Yin, Z Huang, Z Lin, N Mao, B Sun… - Cell death & …, 2020 - nature.com
Ferroptosis is a new type of cell death that was discovered in recent years and is usually
accompanied by a large amount of iron accumulation and lipid peroxidation during the cell …
accompanied by a large amount of iron accumulation and lipid peroxidation during the cell …
Recent progress in ferroptosis inducers for cancer therapy
Ferroptosis is a newly discovered form of regulated cell death that is the nexus between
metabolism, redox biology, and human health. Emerging evidence shows the potential of …
metabolism, redox biology, and human health. Emerging evidence shows the potential of …
Autophagy-dependent ferroptosis: machinery and regulation
Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved cellular
process capable of degrading various biological molecules (eg, protein, glycogen, lipids …
process capable of degrading various biological molecules (eg, protein, glycogen, lipids …
Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis
Ferroptosis is widely involved in degenerative diseases in various tissues including kidney,
liver and brain, and is a targetable vulnerability in multiple primary and therapy-resistant …
liver and brain, and is a targetable vulnerability in multiple primary and therapy-resistant …
[HTML][HTML] NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis
The transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) is a key regulator of
the cellular antioxidant response, controlling the expression of genes that counteract …
the cellular antioxidant response, controlling the expression of genes that counteract …
Targeting ferroptosis to iron out cancer
One of the key challenges in cancer research is how to effectively kill cancer cells while
leaving the healthy cells intact. Cancer cells often have defects in cell death executioner …
leaving the healthy cells intact. Cancer cells often have defects in cell death executioner …
Platelet membrane‐camouflaged magnetic nanoparticles for ferroptosis‐enhanced cancer immunotherapy
Q Jiang, K Wang, X Zhang, B Ouyang, H Liu, Z Pang… - Small, 2020 - Wiley Online Library
Although cancer immunotherapy has emerged as a tremendously promising cancer therapy
method, it remains effective only for several cancers. Photoimmunotherapy (eg …
method, it remains effective only for several cancers. Photoimmunotherapy (eg …
NUPR1 is a critical repressor of ferroptosis
Ferroptosis is a type of iron-dependent regulated cell death, representing an emerging
disease-modulatory mechanism. Transcription factors play multiple roles in ferroptosis …
disease-modulatory mechanism. Transcription factors play multiple roles in ferroptosis …
The application of ferroptosis in diseases
Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …
[HTML][HTML] HO-1-mediated ferroptosis as a target for protection against retinal pigment epithelium degeneration
Z Tang, Y Ju, X Dai, N Ni, Y Liu, D Zhang, H Gao… - Redox biology, 2021 - Elsevier
Oxidative stress-mediated retinal pigment epithelium (RPE) degeneration plays a vital role
in retinal degeneration with irreversible visual impairment, most notably in age-related …
in retinal degeneration with irreversible visual impairment, most notably in age-related …