The hypothalamus is the centre of neuroendocrine regulation of energy homeostasis and
appetite. Maldevelopment of, or damage to, the key hypothalamic nuclei disrupts the …

Background Obesity is a multifactorial chronic disease with a high, increasing worldwide
prevalence. Genetic causes account for 7% of the cases in children with extreme obesity …

The research program on oxytocin started in 1895, when Oliver and Schafer reported that a
substance extracted from the pituitary gland elevates blood pressure when injected …

Neuromedin U (NMU) is a bioactive peptide produced in the gut and in the brain, with a role
in multiple physiological processes. NMU acts by binding and activating two G protein …

In the last decades, new evidence on brain structure and function has been acquired by
morphological investigations based on synergic interactions between biochemical anatomy …

Oxytocin (OT) is a posterior pituitary hormone that, in addition to its role in regulating
childbirth and lactation, also exerts direct regulatory effects on the skeleton through …

Oxytocin (OT) affects many behavioral, psychological, and physiological functions, including
appetite and body weight regulation. Central and peripheral OT levels are markedly affected …

The neuropeptide oxytocin (OT) has emerged as an important anorexigen in the regulation
of food intake and energy balance. It has been shown that the release of OT and activation …

Background Oxytocin (OT) is a hypothalamic neuropeptide involved in diverse physiological
and behavioral functions, including social-based behavior and food intake control. The …

The hypothalamic neuropeptide and hormone oxytocin are of fundamental importance for
maternal, social, and sexual behavior. Deviations in oxytocin levels have also been …