GAGA factor: a multifunctional pioneering chromatin protein

D Chetverina, M Erokhin, P Schedl - Cellular and Molecular Life Sciences, 2021 - Springer
Abstract The Drosophila GAGA factor (GAF) is a multifunctional protein implicated in
nucleosome organization and remodeling, activation and repression of gene expression …

Interdependence between histone marks and steps in Pol II transcription

Z Wang, AG Chivu, LA Choate, EJ Rice, DC Miller… - bioRxiv, 2020 - biorxiv.org
The role of histone modifications in transcription remains incompletely understood. Here we
used experimental perturbations combined with sensitive machine learning tools that infer …

The pioneer factor GAF is essential for zygotic genome activation and chromatin accessibility in the early Drosophila embryo

MM Gaskill, TJ Gibson, ED Larson, MM Harrison - BioRxiv, 2020 - biorxiv.org
Following fertilization, the genomes of the germ cells are reprogrammed to form the
totipotent embryo. Pioneer transcription factors are required for remodeling the chromatin …