Biological and pharmacological aspects of the NK1‐receptor
S Garcia-Recio, P Gascón - BioMed research international, 2015 - Wiley Online Library
The neurokinin 1 receptor (NK‐1R) is the main receptor for the tachykinin family of peptides.
Substance P (SP) is the major mammalian ligand and the one with the highest affinity. SP is …
Substance P (SP) is the major mammalian ligand and the one with the highest affinity. SP is …
The emerging role of substance P/neurokinin-1 receptor signaling pathways in growth and development of tumor cells
Tachykinins (TKs) include an evolutionarily conserved group of small bio-active peptides
which possess a common carboxyl-terminal sequence, Phe-X-Gly-Leu-Met-NH2. TKs also …
which possess a common carboxyl-terminal sequence, Phe-X-Gly-Leu-Met-NH2. TKs also …
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
ERBB receptor transmodulation by heterologous G-protein–coupled receptors (GPCR)
generates functional diversity in signal transduction. Tachykinins are neuropeptides and …
generates functional diversity in signal transduction. Tachykinins are neuropeptides and …
Neuropeptides in Cancer: Friend and Foe?
Neuropeptides are small regulatory molecules found throughout the body, most notably in
the nervous, cardiovascular, and gastrointestinal systems. They serve as neurotransmitters …
the nervous, cardiovascular, and gastrointestinal systems. They serve as neurotransmitters …
Role of hemokinin-1 in health and disease
É Borbély, Z Helyes - Neuropeptides, 2017 - Elsevier
Abstract Hemokinin-1 (HK-1), the newest tachykinin encoded by the Tac4 gene was
discovered in 2000. Its name differs from that of the other members of this peptide family due …
discovered in 2000. Its name differs from that of the other members of this peptide family due …
Blood-forming stem cells are nervous: direct and indirect regulation of immature human CD34+ cells by the nervous system
The nervous system regulates immunity through hormonal and neuronal routes as part of
host defense and repair mechanism. Here, we review the emerging evidence for regulation …
host defense and repair mechanism. Here, we review the emerging evidence for regulation …
[HTML][HTML] 基于生物信息学分析老年骨质疏松差异表达基因及m6A相关蛋白的研究
周子墨, 陈佳慧, 陈森相, 覃森, 黄瑛, 柳达 - 中国医科大学学报, 2022 - html.rhhz.net
目的通过生物信息学方法探讨老年骨质疏松相关基因表达谱及m 6 A 相关蛋白基因表达.
方法检索GEO 数据库获得数据集, 使用R 语言软件分析获得差异表达基因(DEGs) …
方法检索GEO 数据库获得数据集, 使用R 语言软件分析获得差异表达基因(DEGs) …
[PDF][PDF] The role of the nervous system in hematopoietic stem cell mobilization
Hematopoietic stem cells (HSCs) and blood cell progenitors, such as maturing leucocytes,
steadily enter from bone marrow (BM) into the circulation under steady-state conditions, and …
steadily enter from bone marrow (BM) into the circulation under steady-state conditions, and …
Neurokinin receptors as potential targets in breast cancer treatment
P Rameshwar, BY Reddy, KA Trzaska… - Current drug …, 2008 - ingentaconnect.com
Despite recent advances in the diagnoses and treatment of breast cancer, this disease
continues to be a major cause of death. One of the biggest challenges in breast cancer …
continues to be a major cause of death. One of the biggest challenges in breast cancer …
[图书][B] Osteoimmunopathology: evidence-based perspectives from molecular biology to systems biology
F Chiappelli - 2011 - books.google.com
Osteoimmunology pertains to the study of the relationship between the bones, particularly
the bone marrow, and the immune system. This monograph pursues the best available …
the bone marrow, and the immune system. This monograph pursues the best available …