The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

Although intestinal microbiome have been established as an important biomarker and
regulator of cancer development and therapeutic response, less is known about the role of …

Background Lung cancer is the leading cause of cancer-related deaths worldwide (Ferlay et
al., Int J Cancer 136: E359–386, 2015). In addition, lung cancer is associated with the …

Microbiota have emerged as key modulators of both the carcinogenic process and the
immune response against cancer cells, and, thus, it seems to influence the efficacy of …

To identify disease-relevant T cell receptors (TCRs) with shared antigen specificity, we
analyzed 778,938 TCRβ chain sequences from 178 non-small cell lung cancer patients …

The human microbiome confers benefits or disease susceptibility to the human body through
multiple pathways. Disruption of the symbiotic balance of the human microbiome is …

Like other body districts, lungs present a complex bacteria community. An emerging function
of lung microbiota is to promote and maintain a state of immune tolerance, to prevent …

The correlations between microbiota dysbiosis and cancer have gained extensive attention
and been widely explored. As a leading cancer diagnosis worldwide, lung cancer poses a …

Oral microbiota is associated with human diseases including cancer. Emerging evidence
suggests that proton pump inhibitors (PPIs), which allow the oral microbiome to translocate …

Until recently, bacteria have been studied in terms of their roles in infectious diseases and
mainly by using isolation and culture methods. However, in practice, many bacteria existing …