Glycogen synthase kinase-3β (GSK-3β), a serine/threonine protein kinase, has been
reported to show essential roles in molecular pathophysiology of many diseases …

Hemiindigoids comprise a range of natural and synthetic scaffolds that share the same
aromatic hydrocarbon backbone as well as promising biological and optical properties. The …

In our ongoing research to discover natural products with neuroprotective effects,
hyperoside (quercetin 3-O-galactoside) was isolated from Acer tegmentosum, which has …

Objectives: Overproduction of reactive species, notably reactive oxygen (ROS) and nitrogen
(RNS) species, along with the failure of balancing effects of endogenous antioxidant …

The proliferation, migration and inflammation of vascular smooth muscle cells (VSMCs)
contribute to the pathogenesis and progression of several cardiovascular diseases such as …

Wnts and the components of Wnt/β-catenin signaling are widely expressed in midbrain and
required to control the fate specification of dopaminergic (DAergic) neurons, a neuronal …

Sulfuretin, one of the major flavonoid glycosides found in the stem bark of Albizzia julibrissin
and heartwood of Rhus verniciflua, is a known anti-oxidant. We previously demonstrated …

The present review reports a list of approximately 800 compounds which have been used,
tested or proposed for Parkinson's disease (PD) therapy in the year range 2014–2019 …

Objectives. Parkinson's disease (PD) is a common neurodegenerative disease
characterized by the loss of midbrain dopaminergic neurons in the substantia nigra. The …

Abstract Background Cerium oxide nanoparticles (CeO 2 NPs) showed promising effects in
neurodegenerative diseases including some animal models of Parkinsonism. However, the …