Cancer remains the leading cause of death worldwide despite advances in treatment
options for patients. As such, safe and effective therapeutics are required. Short peptides …

Although significant progress has been made in the implementation of new breast cancer
treatments over the last three decades, this neoplasm annually continues to show high …

Peptide–drug conjugates are organic molecules composed of (i) a small drug molecule,(ii) a
peptide and (iii) a linker. The drug molecule is mandatory for the biological action, however …

Receptors for gonadotropin releasing hormone (GnRH) are highly expressed in various
human cancers including breast, ovarian, endometrial, prostate and colorectal cancer …

Background Alizarin and purpurin are di-and trihydroxyanthraquinones derived from Rubia
tinctorum L. Previous pharmacological studies have demonstrated that they exhibit certain …

Gonadotropin releasing hormone-III (GnRH-III), a native isoform of the human GnRH
isolated from sea lamprey, specifically binds to GnRH receptors on cancer cells enabling its …

Abstract Evaluation of in vitro cytotoxicity of several Cu chelating agents-2, 2′-biquinoline,
8-hydroxyquinoline (oxine), ammonium pyrrolidinedithiocarbamate (APDTC), di-2 …

Gonadotropin-releasing hormone (GnRH1) and its receptor (GnRHR1) drive reproduction by
regulating gonadotropins. Another form, GnRH2, and its receptor (GnRHR2), also exist in …

Recently, an increasing amount of evidence indicates that human gonadotropin-releasing
hormone (hGnRH) and its receptor (hGnRHR) are important regulatory components not only …

Cancer is a major health issue adsorbing the attention of a biomedical research. To fight this
disease, new drugs are developed, specifically tailored to target biological pathways or …