A retrospective performance assessment of the developmental neurotoxicity study in support of OECD test guideline 426

SL Makris, K Raffaele, S Allen… - Environmental …, 2009 - ehp.niehs.nih.gov
Objective We conducted a review of the history and performance of developmental
neurotoxicity (DNT) testing in support of the finalization and implementation of Organisation …

Reproductive and teratologic effects of low‐frequency electromagnetic fields: A review of in vivo and in vitro studies using animal models

RL Brent - Teratology, 1999 - Wiley Online Library
In order to evaluate the reproductive risks of low‐frequency electromagnetic fields (EMF), it
is important to include epidemiological and animal studies in the evaluation, as well as the …

Testing methods for developmental neurotoxicity of environmental chemicals

L Claudio, WC Kwa, AL Russell, D Wallinga - Toxicology and Applied …, 2000 - Elsevier
Human brain development is slow and delicate, involving many unique, though interrelated,
cellular events. The fetus and child are often more susceptible to chemical toxins that alter …

Reproductive and teratologic effects of electromagnetic fields

RL Brent, WE Gordon, WR Bennett, DA Beckman - Reproductive toxicology, 1993 - Elsevier
The reproductive risks of electromagnetic fields (EMF) were evaluated based on an
extensive review of the scientific literature pertaining to human epidemiologic studies …

NTP‐CERHR Expert Panel Report on the reproductive and developmental toxicity of amphetamine and methamphetamine

M Golub, L Costa, K Crofton, D Frank… - … Research Part B …, 2005 - Wiley Online Library
The National Toxicology Program (NTP) and the National Institute of Environmental Health
Sciences (NIEHS) established the NTP Center for the Evaluation of Risks to Human …

Neurobehavioral assessment: a survey of use and value in safety assessment studies

LD Middaugh, D Dow-Edwards, AA Li… - Toxicological …, 2003 - academic.oup.com
This report describes the results of a survey designed to evaluate the contribution of F1
neurobehavioral testing to hazard identification and characterization in safety assessment …

Prolonged exposure to low doses of ozone: short-and long-term changes in behavioral performance in mice

A Sorace, L De Acetis, E Alleva, D Santucci - Environmental research, 2001 - Elsevier
Two separate experiments were designed to assess the effects of ozone exposure on
outbred CD-1 mice. In the first experiment, adult males were exposed continuously to O3 at …

Epidermal growth factor has both growth-promoting and growth-inhibiting effects on physical and neurobehavioral development of neonatal mice

G Calamandrei, E Alleva - Brain research, 1989 - Elsevier
The protein molecule epidermal growth factor (EGF) exerts powerful effects on mouse
physical development, since repeated subcutaneous administrations of murine EGF (3.5 …

Ontogeny of muscimol effects on locomotor activity, habituation, and pain reactivity in mice

G Laviola, E Alleva - Psychopharmacology, 1990 - Springer
Three hundred and twenty mouse pups of both sexes of the CD-1 outbred strain received IP
muscimol and were subsequently assessed for locomotor activity (single Varimex 30-min …

Developmental neurotoxicity following premating maternal exposure to hexachlorobenzene in rats

ES Goldey, DH Taylor - Neurotoxicology and teratology, 1992 - Elsevier
The maternal transfer of hexachlorobenzene (HCB) may place the developing organism at
risk. The present study assessed the developmental neurotoxicity of HCB using a battery of …