Cisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is
limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can …

Background Although great achievements have been made in the field of cancer therapy,
chemotherapy and radiotherapy remain the mainstay cancer therapeutic modalities …

The role of N 6-methyladenosine (m6A) modifications in renal diseases is largely unknown.
Here, we characterized the role of N 6-adenosine-methyltransferase-like 3 (METTL3), whose …

Aims: Ischemia-reperfusion injury (IRI)-induced acute kidney injury (IRI-AKI) is characterized
by elevated levels of reactive oxygen species (ROS), mitochondrial dysfunction, and …

Cisplatin is a widely used chemotherapeutic agent used to treat solid tumours, such as
ovarian, head and neck, and testicular germ cell. A known complication of cisplatin …

Due to their unique physicochemical characteristics, 2D materials have attracted more and
more attention in the biomedicine field. Currently, 2D materials-based nanomedicines have …

Reactive oxygen species (ROS) are pervasive signaling molecules in biological systems. In
humans, a lack of ROS causes chronic and extreme bacterial infections, while uncontrolled …

Folic acid‐(FA‐) induced kidney injury is characterized by the tubule damage due to the
disturbance of the antioxidant system and subsequent interstitial fibrosis. FG‐4592 is an …

Although cisplatin is an effective anticancer drug, its clinical application is limited due to
various side effects, especially nephrotoxicity. In this study, we investigated the protective …

Renal ischemia/reperfusion injury (IRI) is a significant challenge in perioperative medicine
and is related to oxidative programmed cell death. However, the role of ferroptosis, a newly …