What are the respiratory effects of e-cigarettes?

JE Gotts, SE Jordt, R McConnell, R Tarran - bmj, 2019 - bmj.com
Electronic cigarettes (e-cigarettes) are alternative, non-combustible tobacco products that
generate an inhalable aerosol containing nicotine, flavors, propylene glycol, and vegetable …

A summary of in vitro and in vivo studies evaluating the impact of e-cigarette exposure on living organisms and the environment

A Merecz-Sadowska, P Sitarek… - International Journal of …, 2020 - mdpi.com
Worldwide use of electronic cigarettes has been rapidly expanding over recent years, but
the long-term effect of e-cigarette vapor exposure on human health and environment is not …

Collecting e‐cigarette aerosols for in vitro applications: A survey of the biomedical literature and opportunities to increase the value of submerged cell culture‐based …

DJ Smart, G Phillips - Journal of Applied Toxicology, 2021 - Wiley Online Library
Electronic nicotine delivery systems (ENDS) are being developed as potentially reduced‐
risk alternatives to the continued use of combustible tobacco products. Because of the …

[HTML][HTML] E-cigarette exposures, respiratory tract infections, and impaired innate immunity: a narrative review

A Kalininskiy, J Kittel, NE Nacca, RS Misra… - … medicine (Hong Kong …, 2021 - ncbi.nlm.nih.gov
Electronic cigarettes (e-cigarettes) are commonly used devices by adolescents and young
adults. Since their introduction, the popularity of e-cigarettes has increased significantly with …

Protease-armed, pathogenic extracellular vesicles link smoking and chronic obstructive pulmonary disease

MC Madison, C Margaroli, KR Genschmer… - American Journal of …, 2023 - atsjournals.org
Rationale: Mounting evidence demonstrates a role for extracellular vesicles (EVs) in driving
lung disorders, such as chronic obstructive pulmonary disease (COPD). Although cigarette …

Evaluation of Cytotoxicity and Oxidative Stress of Whole Aerosol from Vuse Alto ENDS Products

BM Keyser, R Leverette, J Wertman, T Shutsky… - Toxics, 2024 - mdpi.com
Assessment of in vitro cytotoxicity is an important component of tobacco product
toxicological evaluations. However, current methods of regulatory testing involve exposing …

Cigarette smoke preparations, not electronic nicotine delivery system preparations, induce features of lung disease in a 3D lung repeat-dose model

RE Rayner, P Makena, GL Prasad… - American Journal of …, 2021 - journals.physiology.org
Cigarette smoking is a risk factor for several lung diseases, including chronic obstructive
pulmonary disease, cardiovascular disease, and lung cancer. The potential health effects of …

[HTML][HTML] Multi-endpoint analysis of human 3D airway epithelium following repeated exposure to whole electronic vapor product aerosol or cigarette smoke

L Czekala, R Wieczorek, L Simms, F Yu… - Current Research in …, 2021 - Elsevier
Smoking is a cause of serious diseases in smokers including chronic respiratory diseases.
This study aimed to evaluate the tobacco harm reduction (THR) potential of an electronic …

Nicotine aerosols diminish airway CFTR function and mucociliary clearance

LW Rasmussen, D Stanford… - … of Physiology-Lung …, 2023 - journals.physiology.org
Electronic cigarettes (e-cigs) are often promoted as safe alternatives to smoking based on
the faulty perception that inhaling nicotine is safe until other harmful chemicals in cigarette …

Identification of Nicotinic Acetylcholine Receptor for N‐Acetylcysteine to Rescue Nicotine‐induced Injury Using Beating Cilia in Primary Tissue Derived Airway …

Y Zheng, Q Tian, H Yang, Y Cai, J Zhang… - Advanced …, 2024 - Wiley Online Library
Smoking is one of the major contributors to airway injuries. N‐acetylcysteine (NAC) has
been proposed as a treatment or preventive measure for such injuries. However, the exact …