The use of cannabinoids as therapeutic drugs has increased among aging populations
recently. Age-related changes in the endogenous cannabinoid system could influence the …

Synaptic plasticity, including long‐term potentiation (LTP) and long‐term depression (LTD),
is an essential phenomenon in memory formation as well as maintenance along with many …

Alzheimer's disease (AD) represents the most common form of dementia, characterized by
amyloid β (Aβ) plaques and neurofibrillary tangles (NFTs). It is characterized by …

Neuroinflammation mediated by microglia and oxidative stress play pivotal roles in the
development of chronic temporal lobe epilepsy (TLE). We postulated that kainic acid (KA) …

Cannabinoids produce their characteristic effects mainly by binding to two types of G-protein
coupled receptors (GPCRs), the CB1 and CB2 cannabinoid receptors. The CB1 receptor is …

Age-related cognitive and affective disorders pose significant public health challenges.
Notably, emotional and cognitive symptoms co-occur across multiple age-associated …

Background and Purpose Recent research linking choline‐containing lipids to degeneration
of basal forebrain cholinergic neurons in neuropathological states illustrates the challenge …

Brain-derived neurotrophic factor (BDNF) is important in the development and maintenance
of neurons and their plasticity. Hippocampal BDNF has been implicated in Alzheimer's …

Cannabis preparations could be an effective reconsolidation-based treatment for post-
traumatic stress disorder. However, the effects of Δ 9-tetrahydrocannabinol (THC) in fear …

The neurotrophin brain-derived neurotrophic factor (BDNF) is important in development and
maintenance of neurons and their plasticity. Hippocampal BDNF has been implicated …