Despite major advances in prevention and treatment, cardiac and cerebral atherothrombotic
complications still account for substantial morbidity and mortality worldwide. In this context …

Ischemic cardiomyopathy (ICM) is the leading cause of heart failure worldwide, yet the
cellular and molecular signature of this disease is largely unclear. Using single-nucleus …

Myocardial fibrosis is a major determinant of clinical outcomes in heart failure (HF) patients.
It is characterized by the emergence of myofibroblasts and early activation of pro-fibrotic …

Bone morphogenetic protein (BMP) 4 plays a critical role in regulating neuronal and glial
activity in the course of spinal cord injury (SCI). The underlying cause and cellular source of …

Context: Acute myocardial infarction (AMI) is one of the clinical manifestations of coronary
heart disease caused by the cessation of coronary blood flow. The development of the …

Doxorubicin (DOX) is widely used clinically for the treatment of various malignant tumors, but
it is accompanied by severe body toxic reactions, especially cardiac toxicity. This article …

Context: Acute myocardial infarction (AMI) is one of the clinical manifestations of coronary
heart disease caused by the cessation of coronary blood flow. The development of the …