Cancer remains the leading cause of death worldwide despite the enormous efforts that are
made in the development of cancer biology and anticancer therapeutic treatment …

Lung cancer affects over 1. 8 million people worldwide and is the leading cause of cancer
related mortality globally. Currently, diagnosis of lung cancer involves a combination of …

Tumor biopsy is the gold standard for the assessment of clinical biomarkers for treatment.
However, tumors change dynamically in response to therapy, and there remains a need for …

Single-cell analysis has become an established method to study cell heterogeneity and for
rare cell characterization. Despite the high cost and technical constraints, applications are …

Circulating tumour cells (CTCs) have recently been identified as valuable biomarkers for
diagnostic and prognostic evaluations, as well for monitoring therapeutic responses to …

The isolation and analysis of circulating tumor cells (CTC) has the potential to provide
minimally invasive diagnostic, prognostic and predictive information. Widespread clinical …

Over the past decade, novel methods for enrichment and identification of cancer cells
circulating in the blood have been established. Blood-based detection of cancer cells and …

Circulating tumour cells (CTCs) are the metastatic precursors to distant disease in head and
neck cancers (HNCs). Whilst the prognostic and predictive value of single CTCs have been …

Whilst locoregional control of head and neck cancers (HNCs) has improved over the last
four decades, long-term survival has remained largely unchanged. A possible reason for this …

Background Blockade of the PD-1/PD-L1 immune checkpoint pathway is emerging as a
promising immunotherapeutic approach for the management and treatment of head and …