DNA replication origin activation in space and time
M Fragkos, O Ganier, P Coulombe… - Nature reviews Molecular …, 2015 - nature.com
DNA replication begins with the assembly of pre-replication complexes (pre-RCs) at
thousands of DNA replication origins during the G1 phase of the cell cycle. At the G1–S …
thousands of DNA replication origins during the G1 phase of the cell cycle. At the G1–S …
Functional compartmentalization of the nucleus
J Strouboulis, AP Wolffe - Journal of cell science, 1996 - journals.biologists.com
Recent applications of cell biology and molecular genetics have built an image of nuclear
organization in which the molecular machines involved in transcription, RNA processing and …
organization in which the molecular machines involved in transcription, RNA processing and …
[图书][B] Chromatin: structure and function
A Wolffe - 1998 - books.google.com
The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the
remarkable progress in chromatin research over the past three years. It has been …
remarkable progress in chromatin research over the past three years. It has been …
Dynamic organization of DNA replication in mammalian cell nuclei: spatially and temporally defined replication of chromosome-specific alpha-satellite DNA …
RT O'Keefe, SC Henderson, DL Spector - The Journal of cell biology, 1992 - rupress.org
Five distinct patterns of DNA replication have been identified during S-phase in
asynchronous and synchronous cultures of mammalian cells by conventional fluorescence …
asynchronous and synchronous cultures of mammalian cells by conventional fluorescence …
Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35
NJ Bump, M Hackett, M Hugunin, S Seshagiri, K Brady… - Science, 1995 - science.org
The baculovirus antiapoptotic protein p35 inhibited the proteolytic activity of human
interleukin-1β converting enzyme (ICE) and three of its homologs in enzymatic assays …
interleukin-1β converting enzyme (ICE) and three of its homologs in enzymatic assays …
[HTML][HTML] The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts
TR Coleman, PB Carpenter, WG Dunphy - Cell, 1996 - cell.com
We have cloned a Xenopus Cdc6 homolog (Xcdc6) and characterized its role in DNA
replication with Xenopus egg extracts. Immunodepletion of Xcdc6 abolishes chromosomal …
replication with Xenopus egg extracts. Immunodepletion of Xcdc6 abolishes chromosomal …
Chromosomal replication initiates and terminates at random sequences but at regular intervals in the ribosomal DNA of Xenopus early embryos.
We have analysed the replication of the chromosomal ribosomal DNA (rDNA) cluster in
Xenopus embryos before the midblastula transition. Two‐dimensional gel analysis showed …
Xenopus embryos before the midblastula transition. Two‐dimensional gel analysis showed …
Major binding sites for the nuclear import receptor are the internal nucleoporin Nup153 and the adjacent nuclear filament protein Tpr
S Shah, S Tugendreich, D Forbes - The Journal of cell biology, 1998 - rupress.org
A major question in nuclear import concerns the identity of the nucleoporin (s) that interact
with the nuclear localization sequences (NLS) receptor and its cargo as they traverse the …
with the nuclear localization sequences (NLS) receptor and its cargo as they traverse the …
Human replication proteins hCdc21, hCdc46 and P1Mcm3 bind chromatin uniformly before S-phase and are displaced locally during DNA replication
T Krude, C Musahl, RA Laskey… - Journal of cell …, 1996 - journals.biologists.com
Members of the Mcm-protein family have recently been shown to be involved in restricting
DNA replication to a single cycle in Xenopus laevis egg extracts. In this study, we extended …
DNA replication to a single cycle in Xenopus laevis egg extracts. In this study, we extended …
The expression of poly (ADP-ribose) polymerase during differentiation-linked DNA replication reveals that it is a component of the multiprotein DNA replication …
CM Simbulan-Rosenthal, DS Rosenthal, H Hilz… - Biochemistry, 1996 - ACS Publications
3T3-L1 preadipocytes have been shown to exhibit a transient increase in poly (ADP-ribose)
polymerase (PARP) protein and activity, as well as an association of PARP with DNA …
polymerase (PARP) protein and activity, as well as an association of PARP with DNA …